Primary hepatocyte cultures as an in vitro experimental model for the evaluation of pharmacokinetic drug-drug interactions

Adv Pharmacol. 1997:43:103-30. doi: 10.1016/s1054-3589(08)60203-3.

Author

A P Li¹

Affiliation

¹ In Vitro Technologies, Inc., University of Maryland Technology Center, Baltimore 21227, USA.

PMID: 9342174
DOI: 10.1016/s1054-3589(08)60203-3

No abstract available

Publication types

Review

MeSH terms

Animals
Cells, Cultured
Cytochrome P-450 Enzyme Inhibitors
Cytochrome P-450 Enzyme System / biosynthesis
Cytochrome P-450 Enzyme System / metabolism
Drug Interactions*
Enzyme Induction
Humans
Liver / metabolism*
Pharmacokinetics*

Substances

Cytochrome P-450 Enzyme Inhibitors
Cytochrome P-450 Enzyme System