Peroxisome proliferator activated receptors: transcriptional regulators of adipogenesis, lipid metabolism and more..

W Wahli; O Braissant; B Desvergne

doi:10.1016/1074-5521(95)90045-4

Peroxisome proliferator activated receptors: transcriptional regulators of adipogenesis, lipid metabolism and more..

Chem Biol. 1995 May;2(5):261-6. doi: 10.1016/1074-5521(95)90045-4.

Authors

W Wahli¹, O Braissant, B Desvergne

Affiliation

¹ Glaxo Institute for Molecular Biology, Geneva, Switzerland.

PMID: 9383428
DOI: 10.1016/1074-5521(95)90045-4

Abstract

The recent discovery of lipid-activatable transcription factors that regulate the genes controlling lipid metabolism and adipogenesis has provided insight into the way that organisms sense and respond to lipid levels. Identification of the signaling pathways in which these receptors are involved will help us to understand the control of energy balance and the molecular defects underlying its disorders.

Publication types

Review

MeSH terms

Adipose Tissue / physiology*
Animals
Energy Metabolism
Gene Expression Regulation / genetics
Gene Expression Regulation / physiology
Humans
Lipid Metabolism*
Lipids / genetics
Receptors, Cytoplasmic and Nuclear / genetics
Receptors, Cytoplasmic and Nuclear / physiology*
Signal Transduction / physiology
Transcription Factors / genetics
Transcription Factors / physiology*
Transcription, Genetic / genetics
Transcription, Genetic / physiology*

Substances

Lipids
Receptors, Cytoplasmic and Nuclear
Transcription Factors