Correlating partitioning and caco-2 cell permeability of structurally diverse small molecular weight compounds

Pharm Res. 1998 Sep;15(9):1490-4. doi: 10.1023/a:1011930411574.

Authors

M Yazdanian¹, S L Glynn, J L Wright, A Hawi

Affiliation

¹ Department of Pharmaceutics, Boehringer Ingelheim Pharmaceuticals Inc., Ridgefield, Connecticut 06877, USA. myazdanian@bi-pharm.com

PMID: 9755906
DOI: 10.1023/a:1011930411574

No abstract available

MeSH terms

Alkanes
Caco-2 Cells
Cell Membrane Permeability*
Esters
Humans
Hydrogen Bonding
Molecular Weight
Octanols
Pharmacokinetics*
Propylene Glycols
Solvents

Substances

Alkanes
Esters
Octanols
Propylene Glycols
Solvents
propyleneglycol dipelargonate
n-hexadecane