Human cytochrome P450s: selectivity and measurement in vivo

Xenobiotica. 1998 Dec;28(12):1095-128. doi: 10.1080/004982598238859.
No abstract available

Publication types

  • Review

MeSH terms

  • Aryl Hydrocarbon Hydroxylases*
  • Chlorzoxazone / metabolism
  • Chlorzoxazone / pharmacology
  • Cytochrome P-450 CYP1A2 / analysis
  • Cytochrome P-450 CYP1A2 / chemistry
  • Cytochrome P-450 CYP1A2 / metabolism
  • Cytochrome P-450 CYP2D6 / analysis
  • Cytochrome P-450 CYP2D6 / chemistry
  • Cytochrome P-450 CYP2D6 / metabolism
  • Cytochrome P-450 CYP2E1 / analysis
  • Cytochrome P-450 CYP2E1 / chemistry
  • Cytochrome P-450 CYP2E1 / metabolism
  • Cytochrome P-450 CYP3A
  • Cytochrome P-450 Enzyme Inhibitors
  • Cytochrome P-450 Enzyme System / analysis*
  • Cytochrome P-450 Enzyme System / chemistry
  • Cytochrome P-450 Enzyme System / metabolism*
  • Enzyme Inhibitors / pharmacology
  • Humans
  • Isoenzymes
  • Mixed Function Oxygenases / analysis
  • Mixed Function Oxygenases / chemistry
  • Mixed Function Oxygenases / metabolism
  • Phenytoin / metabolism
  • Phenytoin / pharmacology
  • Steroid 16-alpha-Hydroxylase*
  • Steroid Hydroxylases / analysis
  • Steroid Hydroxylases / chemistry
  • Steroid Hydroxylases / metabolism
  • Structure-Activity Relationship
  • Tolbutamide / metabolism
  • Tolbutamide / pharmacology

Substances

  • Cytochrome P-450 Enzyme Inhibitors
  • Enzyme Inhibitors
  • Isoenzymes
  • Phenytoin
  • Cytochrome P-450 Enzyme System
  • Tolbutamide
  • Mixed Function Oxygenases
  • Steroid Hydroxylases
  • Cytochrome P-450 CYP2E1
  • Aryl Hydrocarbon Hydroxylases
  • CYP1A2 protein, human
  • CYP3A protein, human
  • Cytochrome P-450 CYP1A2
  • Cytochrome P-450 CYP2D6
  • Cytochrome P-450 CYP3A
  • Steroid 16-alpha-Hydroxylase
  • Chlorzoxazone