Carlo AA[au] - Search Results

Year	Number of Results
2001	1
2002	1
2003	2
2015	1
2018	1
2019	1
2020	1
2022	1
2023	1
2024	1

1

Synthesis of Deuterated Heterocycles with Me₂NCD(OMe)₂ and Evaluation of the Products for Metabolism by Aldehyde Oxidase.

Choi C, Carlo AA, Cronin CN, Jing K, Kung DW, Liu J, Lombardo VM, Turco AR, Yin J, Yu A, Wright SW. Choi C, et al. Among authors: carlo aa. ACS Med Chem Lett. 2022 Jan 21;13(2):250-256. doi: 10.1021/acsmedchemlett.1c00634. eCollection 2022 Feb 10. ACS Med Chem Lett. 2022. PMID: 35178182 Free PMC article.

2

Characterization and Applications of Permeabilized Hepatocytes in Drug Discovery.

Zhang S, Orozco CC, Tang LWT, Racich J, Carlo AA, Chang G, Tess D, Keefer C, Di L. Zhang S, et al. Among authors: carlo aa. AAPS J. 2024 Mar 28;26(3):38. doi: 10.1208/s12248-024-00907-9. AAPS J. 2024. PMID: 38548986

3

The Comparison of Machine Learning and Mechanistic In Vitro-In Vivo Extrapolation Models for the Prediction of Human Intrinsic Clearance.

Keefer CE, Chang G, Di L, Woody NA, Tess DA, Osgood SM, Kapinos B, Racich J, Carlo AA, Balesano A, Ferguson N, Orozco C, Zueva L, Luo L. Keefer CE, et al. Among authors: carlo aa. Mol Pharm. 2023 Nov 6;20(11):5616-5630. doi: 10.1021/acs.molpharmaceut.3c00502. Epub 2023 Oct 9. Mol Pharm. 2023. PMID: 37812508

4

A Physiologically Based in Silico Tool to Assess the Risk of Drug-Related Crystalluria.

Li Z, Litchfield J, Tess DA, Carlo AA, Eng H, Keefer C, Maurer TS. Li Z, et al. Among authors: carlo aa. J Med Chem. 2020 Jun 25;63(12):6489-6498. doi: 10.1021/acs.jmedchem.9b01995. Epub 2020 Mar 13. J Med Chem. 2020. PMID: 32130005

5

In Vitro-In Vivo Extrapolation of Key Transporter Activity at the Blood-Brain Barrier.

Trapa PE, Troutman MD, Lau TY, Wager TT, Maurer TS, Patel NC, West MA, Umland JP, Carlo AA, Feng B, Liras JL. Trapa PE, et al. Among authors: carlo aa. Drug Metab Dispos. 2019 Apr;47(4):405-411. doi: 10.1124/dmd.118.083279. Epub 2019 Jan 25. Drug Metab Dispos. 2019. PMID: 30683809

6

Discovery of an in Vivo Tool to Establish Proof-of-Concept for MAP4K4-Based Antidiabetic Treatment.

Ammirati M, Bagley SW, Bhattacharya SK, Buckbinder L, Carlo AA, Conrad R, Cortes C, Dow RL, Dowling MS, El-Kattan A, Ford K, Guimarães CR, Hepworth D, Jiao W, LaPerle J, Liu S, Londregan A, Loria PM, Mathiowetz AM, Munchhof M, Orr ST, Petersen DN, Price DA, Skoura A, Smith AC, Wang J. Ammirati M, et al. Among authors: carlo aa. ACS Med Chem Lett. 2015 Oct 6;6(11):1128-33. doi: 10.1021/acsmedchemlett.5b00215. eCollection 2015 Nov 12. ACS Med Chem Lett. 2015. PMID: 26617966 Free PMC article.

7

Allosteric inhibition of fructose-1,6-bisphosphatase by anilinoquinazolines.

Wright SW, Hageman DL, McClure LD, Carlo AA, Treadway JL, Mathiowetz AM, Withka JM, Bauer PH. Wright SW, et al. Among authors: carlo aa. Bioorg Med Chem Lett. 2001 Jan 8;11(1):17-21. doi: 10.1016/s0960-894x(00)00586-2. Bioorg Med Chem Lett. 2001. PMID: 11140724

8

Organic Anion Transporter 2-Mediated Hepatic Uptake Contributes to the Clearance of High-Permeability-Low-Molecular-Weight Acid and Zwitterion Drugs: Evaluation Using 25 Drugs.

Kimoto E, Mathialagan S, Tylaska L, Niosi M, Lin J, Carlo AA, Tess DA, Varma MVS. Kimoto E, et al. Among authors: carlo aa. J Pharmacol Exp Ther. 2018 Nov;367(2):322-334. doi: 10.1124/jpet.118.252049. Epub 2018 Aug 22. J Pharmacol Exp Ther. 2018. PMID: 30135178

9

3-(2-carboxyethyl)-4,6-dichloro-1H-indole-2-carboxylic acid: an allosteric inhibitor of fructose-1,6-bisphosphatase at the AMP site.

Wright SW, Carlo AA, Danley DE, Hageman DL, Karam GA, Mansour MN, McClure LD, Pandit J, Schulte GK, Treadway JL, Wang IK, Bauer PH. Wright SW, et al. Among authors: carlo aa. Bioorg Med Chem Lett. 2003 Jun 16;13(12):2055-8. doi: 10.1016/s0960-894x(03)00310-x. Bioorg Med Chem Lett. 2003. PMID: 12781194

10

Anilinoquinazoline inhibitors of fructose 1,6-bisphosphatase bind at a novel allosteric site: synthesis, in vitro characterization, and X-ray crystallography.

Wright SW, Carlo AA, Carty MD, Danley DE, Hageman DL, Karam GA, Levy CB, Mansour MN, Mathiowetz AM, McClure LD, Nestor NB, McPherson RK, Pandit J, Pustilnik LR, Schulte GK, Soeller WC, Treadway JL, Wang IK, Bauer PH. Wright SW, et al. Among authors: carlo aa. J Med Chem. 2002 Aug 29;45(18):3865-77. doi: 10.1021/jm010496a. J Med Chem. 2002. PMID: 12190310

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