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2001 1
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Page 1
An efficient asymmetric synthesis of an estrogen receptor modulator by sulfoxide-directed borane reduction.
Song ZJ, King AO, Waters MS, Lang F, Zewge D, Bio M, Leazer JL Jr, Javadi G, Kassim A, Tschaen DM, Reamer RA, Rosner T, Chilenski JR, Mathre DJ, Volante RP, Tillyer R. Song ZJ, et al. Among authors: chilenski jr. Proc Natl Acad Sci U S A. 2004 Apr 20;101(16):5776-81. doi: 10.1073/pnas.0307415101. Epub 2004 Apr 12. Proc Natl Acad Sci U S A. 2004. PMID: 15079059 Free PMC article.
Species differential stereoselective oxidation of a methylsulfide metabolite of MK-0767 [(+/-)-5-[(2,4-dioxothiazolidin-5-yl)methyl]-2-methoxy-N-[[(4-trifluoromethyl)phenyl]methyl]benzamide], a peroxisome proliferator-activated receptor dual agonist.
Karanam BV, Welch CJ, Reddy VG, Chilenski J, Biba M, Vincent S. Karanam BV, et al. Among authors: chilenski j. Drug Metab Dispos. 2004 Oct;32(10):1061-8. doi: 10.1124/dmd.104.000224. Epub 2004 Jun 30. Drug Metab Dispos. 2004. PMID: 15229170
Synthesis of enantiomerically pure D-FDOC, an anti-HIV agent.
Mao S, Bouygues M, Welch C, Biba M, Chilenski J, Schinazi RF, Liotta DC. Mao S, et al. Among authors: chilenski j. Bioorg Med Chem Lett. 2004 Oct 4;14(19):4991-4. doi: 10.1016/j.bmcl.2004.07.016. Bioorg Med Chem Lett. 2004. PMID: 15341966