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Page 1
Identification of Novel, Potent, and Orally Available GCN2 Inhibitors with Type I Half Binding Mode.
Fujimoto J, Kurasawa O, Takagi T, Liu X, Banno H, Kojima T, Asano Y, Nakamura A, Nambu T, Hata A, Ishii T, Sameshima T, Debori Y, Miyamoto M, Klein MG, Tjhen R, Sang BC, Levin I, Lane SW, Snell GP, Li K, Kefala G, Hoffman ID, Ding SC, Cary DR, Mizojiri R. Fujimoto J, et al. Among authors: debori y. ACS Med Chem Lett. 2019 Sep 19;10(10):1498-1503. doi: 10.1021/acsmedchemlett.9b00400. eCollection 2019 Oct 10. ACS Med Chem Lett. 2019. PMID: 31620240 Free PMC article.
Correction to: Construction and Functional Evaluation of a Three-Dimensional Blood-Brain Barrier Model Equipped With Human Induced Pluripotent Stem Cell-Derived Brain Microvascular Endothelial Cells.
Kurosawa T, Sako D, Tega Y, Debori Y, Tomihara Y, Aoyama K, Kubo Y, Amano N, Deguchi Y. Kurosawa T, et al. Among authors: debori y. Pharm Res. 2022 Jul;39(7):1661. doi: 10.1007/s11095-022-03264-4. Pharm Res. 2022. PMID: 35441969 Free PMC article. No abstract available.
Design, Synthesis, and Evaluation of 11C-Labeled 3-Acetyl-Indole Derivatives as a Novel Positron Emission Tomography Imaging Agent for Diacylglycerol Kinase Gamma (DGKγ) in Brain.
Hattori Y, Yamasaki T, Ohashi T, Miyanohana Y, Kusumoto T, Maeda R, Miyamoto M, Debori Y, Hata A, Zhang Y, Wakizaka H, Wakabayashi T, Fujinaga M, Yamashita R, Zhang MR, Koike T. Hattori Y, et al. Among authors: debori y. J Med Chem. 2021 Aug 26;64(16):11990-12002. doi: 10.1021/acs.jmedchem.1c00584. Epub 2021 Aug 4. J Med Chem. 2021. PMID: 34347478
Prediction of the overall renal tubular secretion and hepatic clearance of anionic drugs and a renal drug-drug interaction involving organic anion transporter 3 in humans by in vitro uptake experiments.
Watanabe T, Kusuhara H, Watanabe T, Debori Y, Maeda K, Kondo T, Nakayama H, Horita S, Ogilvie BW, Parkinson A, Hu Z, Sugiyama Y. Watanabe T, et al. Among authors: debori y. Drug Metab Dispos. 2011 Jun;39(6):1031-8. doi: 10.1124/dmd.110.036129. Epub 2011 Mar 7. Drug Metab Dispos. 2011. PMID: 21383204
Design, synthesis, and biological activities of novel hexahydropyrazino[1,2-a]indole derivatives as potent inhibitors of apoptosis (IAP) proteins antagonists with improved membrane permeability across MDR1 expressing cells.
Shiokawa Z, Hashimoto K, Saito B, Oguro Y, Sumi H, Yabuki M, Yoshimatsu M, Kosugi Y, Debori Y, Morishita N, Dougan DR, Snell GP, Yoshida S, Ishikawa T. Shiokawa Z, et al. Among authors: debori y. Bioorg Med Chem. 2013 Dec 15;21(24):7938-54. doi: 10.1016/j.bmc.2013.09.067. Epub 2013 Oct 12. Bioorg Med Chem. 2013. PMID: 24169315