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2005 1
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2011 7
2012 8
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20 results

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Page 1
First-in-Human, Healthy Volunteers Integrated Protocol of ETC-206, an Oral Mnk 1/2 Kinase Inhibitor Oncology Drug.
Teneggi V, Novotny-Diermayr V, Lee LH, Yasin M, Yeo P, Ethirajulu K, Gan SBH, Blanchard SE, Nellore R, Umrani DN, Gomeni R, Teck DLW, Li G, Lu QS, Cao Y, Matter A. Teneggi V, et al. Among authors: ethirajulu k. Clin Transl Sci. 2020 Jan;13(1):57-66. doi: 10.1111/cts.12678. Epub 2019 Sep 9. Clin Transl Sci. 2020. PMID: 31343094 Free PMC article. Clinical Trial.
First-in-Human Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of a Rapidly Developed SARS-CoV-2 Therapeutic Antibody, AOD01, in Healthy Adults.
Prativadibhayankaram VS, Lee LS, Lye D, Xiaoying X, Nellore R, Pendharkar V, Hentze H, Guan S, Ayers BJ, Seah SGK, Chye H, Talib NSN, Kaliaperumal N, Ong WY, Wong ZX, Au VB, Alok A, Connolly JE, Boyd-Kirkup JD, Ingram PJ, Hanson BJ, Ethirajulu K, O'Connell D, Chan CEZ. Prativadibhayankaram VS, et al. Among authors: ethirajulu k. Infect Dis Ther. 2022 Oct;11(5):1999-2015. doi: 10.1007/s40121-022-00681-1. Epub 2022 Sep 4. Infect Dis Ther. 2022. PMID: 36058990 Free PMC article.
The Fc-mediated effector functions of a potent SARS-CoV-2 neutralizing antibody, SC31, isolated from an early convalescent COVID-19 patient, are essential for the optimal therapeutic efficacy of the antibody.
Chan CEZ, Seah SGK, Chye H, Massey S, Torres M, Lim APC, Wong SKK, Neo JJY, Wong PS, Lim JH, Loh GSL, Wang D, Boyd-Kirkup JD, Guan S, Thakkar D, Teo GH, Purushotorman K, Hutchinson PE, Young BE, Low JG, MacAry PA, Hentze H, Prativadibhayankara VS, Ethirajulu K, Comer JE, Tseng CK, Barrett ADT, Ingram PJ, Brasel T, Hanson BJ. Chan CEZ, et al. Among authors: ethirajulu k. PLoS One. 2021 Jun 23;16(6):e0253487. doi: 10.1371/journal.pone.0253487. eCollection 2021. PLoS One. 2021. PMID: 34161386 Free PMC article.
2-anilino-4-aryl-8H-purine derivatives as inhibitors of PDK1.
Blanchard S, Soh CK, Lee CP, Poulsen A, Bonday Z, Goh KL, Goh KC, Goh MK, Pasha MK, Wang H, Williams M, Wood JM, Ethirajulu K, Dymock BW. Blanchard S, et al. Among authors: ethirajulu k. Bioorg Med Chem Lett. 2012 Apr 15;22(8):2880-4. doi: 10.1016/j.bmcl.2012.02.058. Epub 2012 Feb 27. Bioorg Med Chem Lett. 2012. PMID: 22437109
VS-5584, a novel and highly selective PI3K/mTOR kinase inhibitor for the treatment of cancer.
Hart S, Novotny-Diermayr V, Goh KC, Williams M, Tan YC, Ong LC, Cheong A, Ng BK, Amalini C, Madan B, Nagaraj H, Jayaraman R, Pasha KM, Ethirajulu K, Chng WJ, Mustafa N, Goh BC, Benes C, McDermott U, Garnett M, Dymock B, Wood JM. Hart S, et al. Among authors: ethirajulu k. Mol Cancer Ther. 2013 Feb;12(2):151-61. doi: 10.1158/1535-7163.MCT-12-0466. Epub 2012 Dec 27. Mol Cancer Ther. 2013. PMID: 23270925 Free PMC article.
20 results