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Page 1
Phenoxyphenyl sulfone N-formylhydroxylamines (retrohydroxamates) as potent, selective, orally bioavailable matrix metalloproteinase inhibitors.
J Med Chem. 2002 Jan 3;45(1):219-32. doi: 10.1021/jm0103920.
J Med Chem. 2002.
PMID: 11754593
Discovery and characterization of the potent, selective and orally bioavailable MMP inhibitor ABT-770.
Curtin ML, Florjancic AS, Heyman HR, Michaelides MR, Garland RB, Holms JH, Steinman DH, Dellaria JF, Gong J, Wada CK, Guo Y, Elmore IB, Tapang P, Albert DH, Magoc TJ, Marcotte PA, Bouska JJ, Goodfellow CL, Bauch JL, Marsh KC, Morgan DW, Davidsen SK.
Curtin ML, et al. Among authors: goodfellow cl.
Bioorg Med Chem Lett. 2001 Jun 18;11(12):1557-60. doi: 10.1016/s0960-894x(01)00032-4.
Bioorg Med Chem Lett. 2001.
PMID: 11412980
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Improving the in vivo duration of 5-lipoxygenase inhibitors: application of an in vitro glucuronosyltransferase assay.
Bouska JJ, Bell RL, Goodfellow CL, Stewart AO, Brooks CD, Carter GW.
Bouska JJ, et al. Among authors: goodfellow cl.
Drug Metab Dispos. 1997 Sep;25(9):1032-8.
Drug Metab Dispos. 1997.
PMID: 9311617
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Biaryl ether retrohydroxamates as potent, long-lived, orally bioavailable MMP inhibitors.
Michaelides MR, Dellaria JF, Gong J, Holms JH, Bouska JJ, Stacey J, Wada CK, Heyman HR, Curtin ML, Guo Y, Goodfellow CL, Elmore IB, Albert DH, Magoc TJ, Marcotte PA, Morgan DW, Davidsen SK.
Michaelides MR, et al. Among authors: goodfellow cl.
Bioorg Med Chem Lett. 2001 Jun 18;11(12):1553-6. doi: 10.1016/s0960-894x(01)00031-2.
Bioorg Med Chem Lett. 2001.
PMID: 11412979
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Aryl ketones as novel replacements for the C-terminal amide bond of succinyl hydroxamate MMP inhibitors.
Sheppard GS, Florjancic AS, Giesler JR, Xu L, Guo Y, Davidsen SK, Marcotte PA, Elmore I, Albert DH, Magoc TJ, Bouska JJ, Goodfellow CL, Morgan DW, Summers JB.
Sheppard GS, et al. Among authors: goodfellow cl.
Bioorg Med Chem Lett. 1998 Nov 17;8(22):3251-6. doi: 10.1016/s0960-894x(98)00597-6.
Bioorg Med Chem Lett. 1998.
PMID: 9873712
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