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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1996 4
1997 4
1998 3
1999 2
2001 1
2005 2
2006 5
2008 2
2009 4
2011 2
2012 6
2013 1
2017 1
2018 3
2019 1
2024 0

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39 results

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Page 1
Advances in Lead Generation.
Holenz J, Stoy P. Holenz J, et al. Bioorg Med Chem Lett. 2019 Feb 15;29(4):517-524. doi: 10.1016/j.bmcl.2018.12.001. Epub 2018 Dec 3. Bioorg Med Chem Lett. 2019. PMID: 30606700 Review.
Toward β-Secretase-1 Inhibitors with Improved Isoform Selectivity.
Johansson P, Kaspersson K, Gurrell IK, Bäck E, Eketjäll S, Scott CW, Cebers G, Thorne P, McKenzie MJ, Beaton H, Davey P, Kolmodin K, Holenz J, Duggan ME, Budd Haeberlein S, Bürli RW. Johansson P, et al. Among authors: holenz j. J Med Chem. 2018 Apr 26;61(8):3491-3502. doi: 10.1021/acs.jmedchem.7b01716. Epub 2018 Apr 10. J Med Chem. 2018. PMID: 29617572
Novel KV7 ion channel openers for the treatment of epilepsy and implications for detrusor tissue contraction.
Seefeld MA, Lin H, Holenz J, Downie D, Donovan B, Fu T, Pasikanti K, Zhen W, Cato M, Chaudhary KW, Brady P, Bakshi T, Morrow D, Rajagopal S, Samanta SK, Madhyastha N, Kuppusamy BM, Dougherty RW, Bhamidipati R, Mohd Z, Higgins GA, Chapman M, Rouget C, Lluel P, Matsuoka Y. Seefeld MA, et al. Among authors: holenz j. Bioorg Med Chem Lett. 2018 Dec 15;28(23-24):3793-3797. doi: 10.1016/j.bmcl.2018.09.036. Epub 2018 Sep 29. Bioorg Med Chem Lett. 2018. PMID: 30327146
The small molecule CLP257 does not modify activity of the K+-Cl- co-transporter KCC2 but does potentiate GABAA receptor activity.
Cardarelli RA, Jones K, Pisella LI, Wobst HJ, McWilliams LJ, Sharpe PM, Burnham MP, Baker DJ, Chudotvorova I, Guyot J, Silayeva L, Morrow DH, Dekker N, Zicha S, Davies PA, Holenz J, Duggan ME, Dunlop J, Mather RJ, Wang Q, Medina I, Brandon NJ, Deeb TZ, Moss SJ. Cardarelli RA, et al. Among authors: holenz j. Nat Med. 2017 Dec 7;23(12):1394-1396. doi: 10.1038/nm.4442. Nat Med. 2017. PMID: 29216042 Free PMC article. No abstract available.
Antiplasmodial activity of mono- and dimeric carbazoles.
Bringmann G, Ledermann A, Holenz J, Kao MT, Busse U, Wu HG, François G. Bringmann G, et al. Among authors: holenz j. Planta Med. 1998 Feb;64(1):54-7. doi: 10.1055/s-2006-957366. Planta Med. 1998. PMID: 9491767
Sulfonimidamides as sulfonamides bioisosteres: rational evaluation through synthetic, in vitro, and in vivo studies with γ-secretase inhibitors.
Sehgelmeble F, Janson J, Ray C, Rosqvist S, Gustavsson S, Nilsson LI, Minidis A, Holenz J, Rotticci D, Lundkvist J, Arvidsson PI. Sehgelmeble F, et al. Among authors: holenz j. ChemMedChem. 2012 Mar 5;7(3):396-9. doi: 10.1002/cmdc.201200014. Epub 2012 Feb 3. ChemMedChem. 2012. PMID: 22307979 No abstract available.
Structural-activity relationship study on C-4 carbon atom of the CB1 antagonist SR141716: synthesis and pharmacological evaluation of 1,2,4-triazole-3-carboxamides.
Jagerovic N, Hernandez-Folgado L, Alkorta I, Goya P, Martín MI, Dannert MT, Alsasua A, Frigola J, Cuberes MR, Dordal A, Holenz J. Jagerovic N, et al. Among authors: holenz j. Eur J Med Chem. 2006 Jan;41(1):114-20. doi: 10.1016/j.ejmech.2005.06.012. Epub 2005 Nov 11. Eur J Med Chem. 2006. PMID: 16289480
39 results