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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1992 1
1994 2
1995 1
1996 2
1997 1
1998 3
1999 3
2000 2
2001 3
2002 3
2003 6
2004 5
2005 5
2006 6
2007 6
2008 5
2009 9
2010 7
2011 12
2012 11
2013 11
2014 8
2015 9
2016 10
2017 9
2018 8
2019 4
2020 8
2021 5
2022 12
2023 5
2024 1

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163 results

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Page 1
An oral SARS-CoV-2 Mpro inhibitor clinical candidate for the treatment of COVID-19.
Owen DR, Allerton CMN, Anderson AS, Aschenbrenner L, Avery M, Berritt S, Boras B, Cardin RD, Carlo A, Coffman KJ, Dantonio A, Di L, Eng H, Ferre R, Gajiwala KS, Gibson SA, Greasley SE, Hurst BL, Kadar EP, Kalgutkar AS, Lee JC, Lee J, Liu W, Mason SW, Noell S, Novak JJ, Obach RS, Ogilvie K, Patel NC, Pettersson M, Rai DK, Reese MR, Sammons MF, Sathish JG, Singh RSP, Steppan CM, Stewart AE, Tuttle JB, Updyke L, Verhoest PR, Wei L, Yang Q, Zhu Y. Owen DR, et al. Among authors: kalgutkar as. Science. 2021 Dec 24;374(6575):1586-1593. doi: 10.1126/science.abl4784. Epub 2021 Nov 2. Science. 2021. PMID: 34726479 Free article.
A Small-Molecule Oral Agonist of the Human Glucagon-like Peptide-1 Receptor.
Griffith DA, Edmonds DJ, Fortin JP, Kalgutkar AS, Kuzmiski JB, Loria PM, Saxena AR, Bagley SW, Buckeridge C, Curto JM, Derksen DR, Dias JM, Griffor MC, Han S, Jackson VM, Landis MS, Lettiere D, Limberakis C, Liu Y, Mathiowetz AM, Patel JC, Piotrowski DW, Price DA, Ruggeri RB, Tess DA. Griffith DA, et al. Among authors: kalgutkar as. J Med Chem. 2022 Jun 23;65(12):8208-8226. doi: 10.1021/acs.jmedchem.1c01856. Epub 2022 Jun 1. J Med Chem. 2022. PMID: 35647711 Free PMC article.
Biotransformation research advances - 2022 year in review.
Khojasteh SC, Argikar UA, Cheruzel L, Cho S, Crouch RD, Dhaware D, Heck CJS, Johnson KM, Kalgutkar AS, King L, Liu J, Ma B, Maw H, Miller GP, Seneviratne HK, Takahashi RH, Wang S, Wei C, Jackson KD. Khojasteh SC, et al. Among authors: kalgutkar as. Drug Metab Rev. 2023 Nov;55(4):301-342. doi: 10.1080/03602532.2023.2262161. Epub 2023 Oct 28. Drug Metab Rev. 2023. PMID: 37737116 Review.
Biotransformation novel advances - 2021 year in review.
Khojasteh SC, Argikar UA, Cho S, Crouch R, Heck CJS, Johnson KM, Kalgutkar AS, King L, Maw HH, Seneviratne HK, Wang S, Wei C, Zhang D, Jackson KD. Khojasteh SC, et al. Among authors: kalgutkar as. Drug Metab Rev. 2022 Aug;54(3):207-245. doi: 10.1080/03602532.2022.2097253. Epub 2022 Aug 30. Drug Metab Rev. 2022. PMID: 35815654 Free PMC article. Review.
Bioactivation and reactivity research advances - 2022 year in review‡.
Wang S, Argikar UA, Cheruzel L, Cho S, Crouch RD, Dhaware D, Heck CJS, Johnson KM, Kalgutkar AS, King L, Liu J, Ma B, Maw H, Miller GP, Seneviratne HK, Takahashi RH, Wei C, Khojasteh SC. Wang S, et al. Among authors: kalgutkar as. Drug Metab Rev. 2023 Nov;55(4):267-300. doi: 10.1080/03602532.2023.2244193. Epub 2023 Aug 22. Drug Metab Rev. 2023. PMID: 37608698 Review.
Small molecule branched-chain ketoacid dehydrogenase kinase (BDK) inhibitors with opposing effects on BDK protein levels.
Roth Flach RJ, Bollinger E, Reyes AR, Laforest B, Kormos BL, Liu S, Reese MR, Martinez Alsina LA, Buzon L, Zhang Y, Bechle B, Rosado A, Sahasrabudhe PV, Knafels J, Bhattacharya SK, Omoto K, Stansfield JC, Hurley LD, Song L, Luo L, Breitkopf SB, Monetti M, Cunio T, Tierney B, Geoly FJ, Delmore J, Siddall CP, Xue L, Yip KN, Kalgutkar AS, Miller RA, Zhang BB, Filipski KJ. Roth Flach RJ, et al. Among authors: kalgutkar as. Nat Commun. 2023 Aug 9;14(1):4812. doi: 10.1038/s41467-023-40536-y. Nat Commun. 2023. PMID: 37558654 Free PMC article.
Structural attributes influencing unbound tissue distribution.
Orozco CC, Atkinson K, Ryu S, Chang G, Keefer C, Lin J, Riccardi K, Mongillo RK, Tess D, Filipski KJ, Kalgutkar AS, Litchfield J, Scott D, Di L. Orozco CC, et al. Among authors: kalgutkar as. Eur J Med Chem. 2020 Jan 1;185:111813. doi: 10.1016/j.ejmech.2019.111813. Epub 2019 Oct 28. Eur J Med Chem. 2020. PMID: 31732255
163 results