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Year Number of Results
1997 1
2000 1
2002 1
2007 1
2010 3
2011 7
2012 1
2014 1
2015 1
2024 0

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17 results

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Page 1
Zwitterionic CRTh2 antagonists.
Luker T, Bonnert R, Paine SW, Schmidt J, Sargent C, Cook AR, Cook A, Gardiner P, Hill S, Weyman-Jones C, Patel A, Thom S, Thorne P. Luker T, et al. J Med Chem. 2011 Mar 24;54(6):1779-88. doi: 10.1021/jm1014549. Epub 2011 Feb 28. J Med Chem. 2011. PMID: 21355602
Deferitazole, a new orally active iron chelator.
Hider RC, Kong X, Abbate V, Harland R, Conlon K, Luker T. Hider RC, et al. Among authors: luker t. Dalton Trans. 2015 Mar 21;44(11):5197-204. doi: 10.1039/c5dt00063g. Dalton Trans. 2015. PMID: 25687725
In silico prediction of acyl glucuronide reactivity.
Potter T, Lewis R, Luker T, Bonnert R, Bernstein MA, Birkinshaw TN, Thom S, Wenlock M, Paine S. Potter T, et al. Among authors: luker t. J Comput Aided Mol Des. 2011 Nov;25(11):997-1005. doi: 10.1007/s10822-011-9479-0. Epub 2011 Oct 26. J Comput Aided Mol Des. 2011. PMID: 22042375
Strategies to improve in vivo toxicology outcomes for basic candidate drug molecules.
Luker T, Alcaraz L, Chohan KK, Blomberg N, Brown DS, Butlin RJ, Elebring T, Griffin AM, Guile S, St-Gallay S, Swahn BM, Swallow S, Waring MJ, Wenlock MC, Leeson PD. Luker T, et al. Bioorg Med Chem Lett. 2011 Oct 1;21(19):5673-9. doi: 10.1016/j.bmcl.2011.07.074. Epub 2011 Jul 27. Bioorg Med Chem Lett. 2011. PMID: 21852131
The discovery of novel, potent and highly selective inhibitors of inducible nitric oxide synthase (iNOS).
Cheshire DR, Åberg A, Andersson GM, Andrews G, Beaton HG, Birkinshaw TN, Boughton-Smith N, Connolly S, Cook TR, Cooper A, Cooper SL, Cox D, Dixon J, Gensmantel N, Hamley PJ, Harrison R, Hartopp P, Käck H, Leeson PD, Luker T, Mete A, Millichip I, Nicholls DJ, Pimm AD, St-Gallay SA, Wallace AV. Cheshire DR, et al. Among authors: luker t. Bioorg Med Chem Lett. 2011 Apr 15;21(8):2468-71. doi: 10.1016/j.bmcl.2011.02.061. Epub 2011 Feb 18. Bioorg Med Chem Lett. 2011. PMID: 21398123
Discovery of potent and selective adamantane-based small-molecule P2X(7) receptor antagonists/interleukin-1beta inhibitors.
Furber M, Alcaraz L, Bent JE, Beyerbach A, Bowers K, Braddock M, Caffrey MV, Cladingboel D, Collington J, Donald DK, Fagura M, Ince F, Kinchin EC, Laurent C, Lawson M, Luker TJ, Mortimore MM, Pimm AD, Riley RJ, Roberts N, Robertson M, Theaker J, Thorne PV, Weaver R, Webborn P, Willis P. Furber M, et al. Among authors: luker tj. J Med Chem. 2007 Nov 29;50(24):5882-5. doi: 10.1021/jm700949w. Epub 2007 Oct 27. J Med Chem. 2007. PMID: 17963373
17 results