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Time-dependent pharmacokinetics and drug metabolism of atovaquone plus proguanil (Malarone) when taken as chemoprophylaxis.
Eur J Clin Pharmacol. 2002 Apr;58(1):19-27. doi: 10.1007/s00228-002-0426-9. Epub 2002 Feb 28.
Eur J Clin Pharmacol. 2002.
PMID: 11956669
Clinical Trial.
Characterization and partial purification of the rat and human enzyme systems active in the reduction of N-hydroxymelagatran and benzamidoxime.
Andersson S, Hofmann Y, Nordling A, Li XQ, Nivelius S, Andersson TB, Ingelman-Sundberg M, Johansson I.
Andersson S, et al. Among authors: nivelius s.
Drug Metab Dispos. 2005 Apr;33(4):570-8. doi: 10.1124/dmd.104.002972. Epub 2005 Jan 7.
Drug Metab Dispos. 2005.
PMID: 15640373
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