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Characterization of primary human hepatocyte spheroids as a model system for drug-induced liver injury, liver function and disease.
Bell CC, Hendriks DF, Moro SM, Ellis E, Walsh J, Renblom A, Fredriksson Puigvert L, Dankers AC, Jacobs F, Snoeys J, Sison-Young RL, Jenkins RE, Nordling Å, Mkrtchian S, Park BK, Kitteringham NR, Goldring CE, Lauschke VM, Ingelman-Sundberg M. Bell CC, et al. Among authors: nordling a. Sci Rep. 2016 May 4;6:25187. doi: 10.1038/srep25187. Sci Rep. 2016. PMID: 27143246 Free PMC article.
Clinically Relevant Cytochrome P450 3A4 Induction Mechanisms and Drug Screening in Three-Dimensional Spheroid Cultures of Primary Human Hepatocytes.
Hendriks DFG, Vorrink SU, Smutny T, Sim SC, Nordling Å, Ullah S, Kumondai M, Jones BC, Johansson I, Andersson TB, Lauschke VM, Ingelman-Sundberg M. Hendriks DFG, et al. Among authors: nordling a. Clin Pharmacol Ther. 2020 Oct;108(4):844-855. doi: 10.1002/cpt.1860. Epub 2020 May 22. Clin Pharmacol Ther. 2020. PMID: 32320483
15 results