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Equivalent steady-state pharmacokinetics of lamivudine in plasma and lamivudine triphosphate within cells following administration of lamivudine at 300 milligrams once daily and 150 milligrams twice daily.
Yuen GJ, Lou Y, Bumgarner NF, Bishop JP, Smith GA, Otto VR, Hoelscher DD. Yuen GJ, et al. Among authors: otto vr. Antimicrob Agents Chemother. 2004 Jan;48(1):176-82. doi: 10.1128/AAC.48.1.176-182.2004. Antimicrob Agents Chemother. 2004. PMID: 14693537 Free PMC article. Clinical Trial.