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Establishment of a Drug-Induced, Bile Acid-Dependent Hepatotoxicity Model Using HepaRG Cells.
J Pharm Sci. 2016 Apr;105(4):1550-60. doi: 10.1016/j.xphs.2016.01.013. Epub 2016 Mar 4.
J Pharm Sci. 2016.
PMID: 26952880
Metabolic Activation of Cholestatic Drug-Induced Bile Acid-Dependent Toxicity in Human Sandwich-Cultured Hepatocytes.
Ogimura E, Tokizono M, Sekine S, Nakagawa T, Bando K, Ito K.
Ogimura E, et al. Among authors: tokizono m.
J Pharm Sci. 2017 Sep;106(9):2509-2514. doi: 10.1016/j.xphs.2017.04.050. Epub 2017 Apr 30.
J Pharm Sci. 2017.
PMID: 28465153
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Prediction of the Clinical Risk of Drug-Induced Cholestatic Liver Injury Using an In Vitro Sandwich Cultured Hepatocyte Assay.
Susukida T, Sekine S, Nozaki M, Tokizono M, Ito K.
Susukida T, et al. Among authors: tokizono m.
Drug Metab Dispos. 2015 Nov;43(11):1760-8. doi: 10.1124/dmd.115.065425. Epub 2015 Sep 1.
Drug Metab Dispos. 2015.
PMID: 26329788
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