Vildhede A[au] - Search Results

Year	Number of Results
2012	1
2014	1
2015	1
2016	3
2017	4
2018	5
2019	1
2020	2
2021	3
2022	1
2023	1
2024	1

1

Understanding Statin-Roxadustat Drug-Drug-Disease Interaction Using Physiologically-Based Pharmacokinetic Modeling.

Dong J, Prieto Garcia L, Huang Y, Tang W, Lundahl A, Elebring M, Ahlström C, Vildhede A, Sjögren E, Någård M. Dong J, et al. Among authors: vildhede a. Clin Pharmacol Ther. 2023 Oct;114(4):825-835. doi: 10.1002/cpt.2980. Epub 2023 Jul 13. Clin Pharmacol Ther. 2023. PMID: 37376792

2

Hepatocyte size fractionation allows dissection of human liver zonation.

Ölander M, Wegler C, Flörkemeier I, Treyer A, Handin N, Pedersen JM, Vildhede A, Mateus A, LeCluyse EL, Urdzik J, Artursson P. Ölander M, et al. Among authors: vildhede a. J Cell Physiol. 2021 Aug;236(8):5885-5894. doi: 10.1002/jcp.30273. Epub 2021 Jan 16. J Cell Physiol. 2021. PMID: 33452735

3

In Vitro Assessment of the Drug-Drug Interaction Potential of Verinurad and Its Metabolites as Substrates and Inhibitors of Metabolizing Enzymes and Drug Transporters.

Gopaul VS, Vildhede A, Andersson TB, Erlandsson F, Lee CA, Johansson S, Hilgendorf C. Gopaul VS, et al. Among authors: vildhede a. J Pharmacol Exp Ther. 2021 Aug;378(2):108-123. doi: 10.1124/jpet.121.000549. Epub 2021 Jun 1. J Pharmacol Exp Ther. 2021. PMID: 34074714

4

Gene-by-Environment Interaction of Bcrp^-/- and Methionine- and Choline-Deficient Diet-Induced Nonalcoholic Steatohepatitis Alters SN-38 Disposition.

Toth EL, Li H, Dzierlenga AL, Clarke JD, Vildhede A, Goedken M, Cherrington NJ. Toth EL, et al. Among authors: vildhede a. Drug Metab Dispos. 2018 Nov;46(11):1478-1486. doi: 10.1124/dmd.118.082081. Epub 2018 Aug 30. Drug Metab Dispos. 2018. PMID: 30166404 Free PMC article.

5

Primary Human Hepatocyte Spheroid Model as a 3D In Vitro Platform for Metabolism Studies.

Kanebratt KP, Janefeldt A, Vilén L, Vildhede A, Samuelsson K, Milton L, Björkbom A, Persson M, Leandersson C, Andersson TB, Hilgendorf C. Kanebratt KP, et al. Among authors: vildhede a. J Pharm Sci. 2021 Jan;110(1):422-431. doi: 10.1016/j.xphs.2020.10.043. Epub 2020 Oct 26. J Pharm Sci. 2021. PMID: 33122050 Free article.

6

Mechanistic Modeling of Pitavastatin Disposition in Sandwich-Cultured Human Hepatocytes: A Proteomics-Informed Bottom-Up Approach.

Vildhede A, Mateus A, Khan EK, Lai Y, Karlgren M, Artursson P, Kjellsson MC. Vildhede A, et al. Drug Metab Dispos. 2016 Apr;44(4):505-16. doi: 10.1124/dmd.115.066746. Epub 2016 Feb 3. Drug Metab Dispos. 2016. PMID: 26842596

7

Organic Anion Transporter 2 Mediates Hepatic Uptake of Tolbutamide, a CYP2C9 Probe Drug.

Bi YA, Mathialagan S, Tylaska L, Fu M, Keefer J, Vildhede A, Costales C, Rodrigues AD, Varma MVS. Bi YA, et al. Among authors: vildhede a. J Pharmacol Exp Ther. 2018 Mar;364(3):390-398. doi: 10.1124/jpet.117.245951. Epub 2018 Jan 11. J Pharmacol Exp Ther. 2018. PMID: 29326367

8

Quantitative Proteomics and Mechanistic Modeling of Transporter-Mediated Disposition in Nonalcoholic Fatty Liver Disease.

Vildhede A, Kimoto E, Pelis RM, Rodrigues AD, Varma MVS. Vildhede A, et al. Clin Pharmacol Ther. 2020 May;107(5):1128-1137. doi: 10.1002/cpt.1699. Epub 2019 Dec 26. Clin Pharmacol Ther. 2020. PMID: 31630405

9

In-depth quantitative analysis and comparison of the human hepatocyte and hepatoma cell line HepG2 proteomes.

Wiśniewski JR, Vildhede A, Norén A, Artursson P. Wiśniewski JR, et al. Among authors: vildhede a. J Proteomics. 2016 Mar 16;136:234-47. doi: 10.1016/j.jprot.2016.01.016. Epub 2016 Jan 26. J Proteomics. 2016. PMID: 26825538 Free article.

10

Does the choice of applied physiologically-based pharmacokinetics platform matter? A case study on simvastatin disposition and drug-drug interaction.

Prieto Garcia L, Lundahl A, Ahlström C, Vildhede A, Lennernäs H, Sjögren E. Prieto Garcia L, et al. Among authors: vildhede a. CPT Pharmacometrics Syst Pharmacol. 2022 Sep;11(9):1194-1209. doi: 10.1002/psp4.12837. Epub 2022 Jul 16. CPT Pharmacometrics Syst Pharmacol. 2022. PMID: 35722750 Free PMC article.

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