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Page 1
Immobilized Cytochrome P450 for Monitoring of P450-P450 Interactions and Metabolism.
Drug Metab Dispos. 2016 May;44(5):741-9. doi: 10.1124/dmd.115.067637. Epub 2016 Mar 9.
Drug Metab Dispos. 2016.
PMID: 26961240
Free PMC article.
Measurement of electron transfer through cytochrome P450 protein on nanopillars and the effect of bound substrates.
Jett JE, Lederman D, Wollenberg LA, Li D, Flora DR, Bostick CD, Tracy TS, Gannett PM.
Jett JE, et al. Among authors: wollenberg la.
J Am Chem Soc. 2013 Mar 13;135(10):3834-40. doi: 10.1021/ja309104g. Epub 2013 Mar 4.
J Am Chem Soc. 2013.
PMID: 23427827
Free PMC article.
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A Next-Generation TRK Kinase Inhibitor Overcomes Acquired Resistance to Prior TRK Kinase Inhibition in Patients with TRK Fusion-Positive Solid Tumors.
Drilon A, Nagasubramanian R, Blake JF, Ku N, Tuch BB, Ebata K, Smith S, Lauriault V, Kolakowski GR, Brandhuber BJ, Larsen PD, Bouhana KS, Winski SL, Hamor R, Wu WI, Parker A, Morales TH, Sullivan FX, DeWolf WE, Wollenberg LA, Gordon PR, Douglas-Lindsay DN, Scaltriti M, Benayed R, Raj S, Hanusch B, Schram AM, Jonsson P, Berger MF, Hechtman JF, Taylor BS, Andrews S, Rothenberg SM, Hyman DM.
Drilon A, et al. Among authors: wollenberg la.
Cancer Discov. 2017 Sep;7(9):963-972. doi: 10.1158/2159-8290.CD-17-0507. Epub 2017 Jun 3.
Cancer Discov. 2017.
PMID: 28578312
Free PMC article.
Clinical Trial.
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Selective filling of nanowells in nanowell arrays fabricated using polystyrene nanosphere lithography with cytochrome P450 enzymes.
Wollenberg LA, Jett JE, Wu Y, Flora DR, Wu N, Tracy TS, Gannett PM.
Wollenberg LA, et al.
Nanotechnology. 2012 Sep 28;23(38):385101. doi: 10.1088/0957-4484/23/38/385101. Epub 2012 Sep 4.
Nanotechnology. 2012.
PMID: 22947619
Free PMC article.
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An exploratory, randomized, parallel-group, open-label, relative bioavailability study with an additional two-period crossover food-effect study exploring the pharmacokinetics of two novel formulations of pexmetinib (ARRY-614).
Wollenberg LA, Corson DT, Nugent CA, Peterson FL, Ptaszynski AM, Arrigo A, Mannila CG, Litwiler KS, Bell SJ.
Wollenberg LA, et al.
Clin Pharmacol. 2015 Sep 30;7:87-95. doi: 10.2147/CPAA.S83871. eCollection 2015.
Clin Pharmacol. 2015.
PMID: 26491375
Free PMC article.
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The use of immobilized cytochrome P4502C9 in PMMA-based plug flow bioreactors for the production of drug metabolites.
Wollenberg LA, Kabulski JL, Powell MJ, Chen J, Flora DR, Tracy TS, Gannett PM.
Wollenberg LA, et al.
Appl Biochem Biotechnol. 2014 Feb;172(3):1293-306. doi: 10.1007/s12010-013-0537-z. Epub 2013 Oct 30.
Appl Biochem Biotechnol. 2014.
PMID: 24166101
Free PMC article.
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