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In vitro methods to study intestinal drug metabolism.
van de Kerkhof EG, de Graaf IA, Groothuis GM. van de Kerkhof EG, et al. Curr Drug Metab. 2007 Oct;8(7):658-75. doi: 10.2174/138920007782109742. Curr Drug Metab. 2007. PMID: 17979654 Review.
Biodistribution and metabolism studies of lipid nanoparticle-formulated internally [3H]-labeled siRNA in mice.
Christensen J, Litherland K, Faller T, van de Kerkhof E, Natt F, Hunziker J, Boos J, Beuvink I, Bowman K, Baryza J, Beverly M, Vargeese C, Heudi O, Stoeckli M, Krauser J, Swart P. Christensen J, et al. Among authors: van de kerkhof e. Drug Metab Dispos. 2014 Mar;42(3):431-40. doi: 10.1124/dmd.113.055434. Epub 2014 Jan 3. Drug Metab Dispos. 2014. PMID: 24389421
Whole-body scanning PCR; a highly sensitive method to study the biodistribution of mRNAs, noncoding RNAs and therapeutic oligonucleotides.
Boos JA, Kirk DW, Piccolotto ML, Zuercher W, Gfeller S, Neuner P, Dattler A, Wishart WL, Von Arx F, Beverly M, Christensen J, Litherland K, van de Kerkhof E, Swart PJ, Faller T, Beyerbach A, Morrissey D, Hunziker J, Beuvink I. Boos JA, et al. Among authors: van de kerkhof e. Nucleic Acids Res. 2013 Aug;41(15):e145. doi: 10.1093/nar/gkt515. Epub 2013 Jun 13. Nucleic Acids Res. 2013. PMID: 23766292 Free PMC article.
12 results