This study was carried out to assess the relationship between turpentine-induced elevation
of seromucoids and drug metabolism. Six groups of rats were used; one of them received I ml …

To investigate factors influencing cell proliferation, cells are often cultured in serum-free
medium. In the present study it is shown that addition of zinc chloride (40 μM) to primary mouse …

Effects of 3,4,3′,4′-tetrachlorobiphenyl (TCB) on glucose-6-phosphatase (G6Pase)-altered
hepatic foci of N-nitrosomorpholine (NNM)-treated B6C3F1 mice were investigated. TCB …

The administration of ketones potentiates CCl 4 hepatotoxicity; however, the potencies of
the ketones differ. The aim of the present study was to assess potential differences between …

Naphthol was conjugated in tissue pieces of the gastric wall to naphthol glucuronide (85%)
and naphthol sulfate (15%). There was no regioselectivity in different parts of the stomach. In …

The protective effect of diltiazem on acetaminophen and phalloidine hepatotoxicity has been
studied in male CD-1 mice. Groups of 8 mice each received 0.9% NaCl or 6, 12, 18 and 24 …

The prevalence of atypical cytology has been determined in relation to age, smoking and
asbestos exposure for male workers employed in 3 mines in the Province of Quebec. Overall …

UDP-glucuronosyltransferase (UDPGT) was studied immunohistochemically in hepatic foci
and nodules of N-nitrosomorpholine-treated mice. Serial sections were stained for glucose-6-…

There is evidence suggesting that regular physical activity enhances hepatic metabolism of
such low clearance drugs as aminopyrine and antipyrine (1). Nutrition (or malnutrition) can …

P450IIE1 was studied in rat hepatocyte foci and nodules from male Wistar rats, treated for 7
weeks with N-nitrosomorpholine (20, 40 and 80 mg/ml of drinking water). Livers were …