Cocaine disposition in humans after intravenous injection, nasal insufflation (snorting), or smoking.

AR Jeffcoat, M Perez-Reyes, JM Hill, BM Sadler… - Drug Metabolism and …, 1989 - ASPET
The disposition of radiolabeled cocaine in humans has been studied after three routes of
administration: iv injection, nasal insufflation (ni, snorting), and smoke inhalation (si). …

[PDF][PDF] Pharmacokinetics of methamphetamine self-administered to human subjects by smoking S-(+)-methamphetamine hydrochloride.

CE Cook, AR Jeffcoat, JM Hill, DE Pugh… - Drug Metabolism and …, 1993 - researchgate.net
S-(+)-methamphetamine hydrochloride(“ice”) is abused by smoking (inhaling the vapors of
the material). Male human volunteers inhaled the drug from a pipe heated at 300#{176}-305#{…

Sustained drug delivery systems. I. The permeability of poly(ϵ‐caprolactone), poly(DL‐lactic acid), and their copolymers

CG Pitt, AR Jeffcoat, RA Zweidinger… - Journal of biomedical …, 1979 - Wiley Online Library
The maximum steady state flux, diffusion coefficients, and solubilities of five contraceptive
steroids in homopolymers and copolymers of ϵ‐caprolactone and DL‐lactic acid were …

[HTML][HTML] Clinical characteristics and pharmacokinetics of purified soy isoflavones: single-dose administration to healthy men

MG Busby, AR Jeffcoat, LAT Bloedon, MA Koch… - The American journal of …, 2002 - Elsevier
… Author links open overlay panel Marjorie G Busby , A Robert Jeffcoat , LeAnne T Bloedon ,
Matthew A Koch , Tracy Black , Kelly J Dix , William D Heizer , Brian F Thomas , Judith M Hill , …

Metabolism, disposition and excretion of [14C] melamine in male Fischer 344 rats

RW Mast, AR Jeffcoat, BM Sadler, RC Kraska… - Food and Chemical …, 1983 - Elsevier
The metabolism, excretion and disposition of melamine were determined after administration
of a single oral dose of 0.025 mCi (0.38 mg) [ 14 C]melamine to adult male Fischer 344 rats…

[HTML][HTML] Safety and pharmacokinetics of purified soy isoflavones: single-dose administration to postmenopausal women

LAT Bloedon, AR Jeffcoat, W Lopaczynski… - The American journal of …, 2002 - Elsevier
Background: Soy isoflavones are being evaluated as chemopreventive agents for breast and
other cancers. Objective: The objective was to perform safety and pharmacokinetic studies …

Sustained drug delivery systems II: Factors affecting release rates from poly (ε‐caprolactone) and related biodegradable polyesters

CG Pitt, MM Gratzl, AR Jeffcoat… - Journal of …, 1979 - Wiley Online Library
The release rates of several steroids from films and capsules of homopolymers and copolymers
of ε‐caprolactone, DL‐lactic acid, and glycolic acid were measured in vitro and in vivo …

Pharmacokinetics of oral methamphetamine and effects of repeated daily dosing in humans.

CE Cook, AR Jeffcoat, BM Sadler, JM Hill… - Drug metabolism and …, 1992 - ASPET
The pharmacokinetics of orally administered S-(+)-methamphetamine-d3 were investigated
in human male volunteers before and after a 13-day course of a slow release form of S-…

Ethanol/cocaine interaction: cocaine and cocaethylene plasma concentrations and their relationship to subjective and cardiovascular effects

M Perez-Reyes, AR Jeffcoat - Life sciences, 1992 - Elsevier
To investigate the pharmacologic effects of the interaction between ethanol and cocaine,
eleven male, paid volunteers familiar with the use of both ethanol and cocaine were tested in a …

Clinical characteristics and pharmacokinetics of purified soy isoflavones: multiple-dose administration to men with prostate neoplasia

L Fischer, C Mahoney, AR Jeffcoat, MA Koch… - Nutrition and …, 2004 - Taylor & Francis
A phase I clinical trial was conducted to determine the safety, pharmacokinetic parameters,
and efficacy of orally administered isoflavones (genistein and daidzein, potential cancer …