New service development: a review of the literature and annotated bibliography

A Johne, C Storey - European journal of Marketing, 1998 - emerald.com
Provides a review and ready reference to recent writings on new service development (NSD),
especially for the financial services sector. Discusses the types of new service …

Multidisciplinary research priorities for the COVID-19 pandemic: a call for action for mental health science

…, RC Silver, I Everall, T Ford, A John… - The lancet …, 2020 - thelancet.com
The coronavirus disease 2019 (COVID-19) pandemic is having a profound effect on all
aspects of society, including mental health and physical health. We explore the psychological, …

Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and …

…, HP Arnold, J Brockmöller, A Johne… - Proceedings of the …, 2000 - National Acad Sciences
To evaluate whether alterations in the multidrug-resistance (MDR)-1 gene correlate with
intestinal MDR-1 expression and uptake of orally administered P-glycoprotein (PGP) substrates, …

Pharmacokinetic interaction of digoxin with an herbal extract from St John's wort (Hypericum perforatum)

A Johne, J Brockmöller, S Bauer… - Clinical …, 1999 - Wiley Online Library
Objective Extracts of St John's wort (Hypericum perforatum) are widely used in the treatment
of depression, often as an over‐the‐counter drug. In contrast to its frequent use, knowledge …

[HTML][HTML] Tepotinib in Non–Small-Cell Lung Cancer with MET Exon 14 Skipping Mutations

…, C Stroh, R Bruns, J Straub, A Johne… - … England Journal of …, 2020 - Mass Medical Soc
Background A splice-site mutation that results in a loss of transcription of exon 14 in the
oncogenic driver MET occurs in 3 to 4% of patients with non–small-cell lung cancer (NSCLC). …

Frequency of single nucleotide polymorphisms in the P‐glycoprotein drug transporter MDR1 gene in white subjects

I Cascorbi, T Gerloff, A Johne, C Meisel… - Clinical …, 2001 - Wiley Online Library
Background P‐glycoprotein, the gene product of MDR1, confers multidrug resistance against
antineoplastic agents but also plays an important role in the bioavailability of common …

Tepotinib plus gefitinib in patients with EGFR-mutant non-small-cell lung cancer with MET overexpression or MET amplification and acquired resistance to previous …

…, DSW Tan, R Bruns, J Straub, A Johne… - The Lancet …, 2020 - thelancet.com
Background We evaluated the efficacy and safety of tepotinib, a potent and highly selective
oral MET inhibitor, plus gefitinib in patients with epidermal growth factor receptor (EGFR)-…

Successful market innovation

A Johne - Innovationsmanagement, 1999 - Springer
Amalgamations and take-overs are currently popular among European companies. However,
organic growth remains the engine of long term corporate success. Organic growth relies …

Food production shocks across land and sea

…, A Fleming, EA Fulton, S Hornborg, A Johne… - Nature …, 2019 - nature.com
Sudden losses to food production (that is, shocks) and their consequences across land and
sea pose cumulative threats to global sustainability. We conducted an integrated …

Modulation of steady‐state kinetics of digoxin by haplotypes of the P‐glycoprotein MDR1 gene

A Johne, K Köpke, T Gerloff, I Mai… - Clinical …, 2002 - Wiley Online Library
Objective We investigated the effect of polymorphisms in the P‐glycoprotein (P‐gp) MDR1
gene on steady‐state pharmacokinetics of digoxin in Caucasians. According to earlier data, …