The sulphation of bile acids is an important pathway for the detoxification and elimination of
bile acids during cholestatic liver disease. A dehydroepiandrosterone (DHEA) …

UDP–Glucuronosyltransferases (UGTs) are glycoproteins localized in the endoplasmic
reticulum (ER) which catalyze the conjugation of a broad variety of lipophilic aglycon substrates …

K2 or Spice products are emerging drugs of abuse that contain synthetic cannabinoids (SCBs).
Although assumed by many teens and first time drug users to be a “safe” and “legal” …

Bile acids (BAS) are essential for the effective functioning of mammalian organisms. Their
crucial importance is manifested in solubilization of lipids in bile, micelle formation to facilitate …

A proposal is made for a system of nomenclature of the more common unconjugated and
conjugated bile acids. Acceptable trivial names for bile acids are tabulated, and guidelines are …

Hepatic hydroxylation is an essential step in the metabolism and excretion of bile acids and
is necessary to avoid pathologic conditions such as cholestasis and liver damage. In this …

Through a multiplex promoter spanning 218 kb, the phase II UDP-glucuronosyltransferase
1A (UGT1) gene encodes at least eight differently regulated mRNAs whose protein products …

Monospecific polyclonal antibodies were raised against a variable amino-terminal domain (amino
acids 14-150) of a human liver form of UDP-glucuronosyl-transferase conjugating bile …

Human UDP-glucuronosyltransferases (UGT) are the dominant phase II conjugative drug
metabolism enzymes that also play a central role in processing a range of endobiotic …

Abuse of synthetic cannabinoids (SCs), such as [1-naphthalenyl-(1-pentyl-1H-indol-3-yl]-methanone
(JWH-018) and [1-(5-fluoropentyl)-1H-indol-3-yl]-1-naphthalenyl-methanone (…