Iminosugars and relatives as antiviral and potential anti-infective agents
P Greimel, J Spreitz, AE Stutz… - Current topics in …, 2003 - ingentaconnect.com
Iminosugars have emerged in the literature during mid-1960's as synthetic compounds.
Around the same time, the first examples were found in Nature and their interesting enzyme …
Around the same time, the first examples were found in Nature and their interesting enzyme …
Activation and regulation of the inflammasomes
Inflammasomes are key signalling platforms that detect pathogenic microorganisms and
sterile stressors, and that activate the highly pro-inflammatory cytokines interleukin-1β (IL-1β) …
sterile stressors, and that activate the highly pro-inflammatory cytokines interleukin-1β (IL-1β) …
The 3′ untranslated region of messenger RNA: a molecular 'hotspot'for pathology?
B Conne, A Stutz, JD Vassalli - Nature medicine, 2000 - nature.com
The role of the 3′ untranslated region in posttranscriptional regulation of mRNA expression
is being elucidated. Here we describe diseases arising from anomalies in this region, that …
is being elucidated. Here we describe diseases arising from anomalies in this region, that …
Percutaneous absorption of drugs used in atopic eczema: pimecrolimus permeates less through skin than corticosteroids and tacrolimus
A Billich, H Aschauer, A Aszódi, A Stuetz - International journal of …, 2004 - Elsevier
For treatment of skin diseases with topical drugs, penetration of the agents into the relevant
layers of the skin is required. Permeation through the skin should, however, be kept to a …
layers of the skin is required. Permeation through the skin should, however, be kept to a …
[HTML][HTML] An integrated map of structural variation in 2,504 human genomes
Structural variants are implicated in numerous diseases and make up the majority of varying
nucleotides among human genomes. Here we describe an integrated set of eight structural …
nucleotides among human genomes. Here we describe an integrated set of eight structural …
NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice
Alzheimer’s disease is the world’s most common dementing illness. Deposition of amyloid-β
peptide drives cerebral neuroinflammation by activating microglia 1 , 2 . Indeed, amyloid-β …
peptide drives cerebral neuroinflammation by activating microglia 1 , 2 . Indeed, amyloid-β …
Cutting edge: NF-κB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression
FG Bauernfeind, G Horvath, A Stutz… - The Journal of …, 2009 - journals.aai.org
The IL-1 family cytokines are regulated on transcriptional and posttranscriptional levels.
Pattern recognition and cytokine receptors control pro-IL-1β transcription whereas …
Pattern recognition and cytokine receptors control pro-IL-1β transcription whereas …
Search for neutrino oscillations at 15, 40 and 95 meters from a nuclear power reactor at Bugey
…, E Nagy, H Pessard, F Pierre, M Obolensky, A Stutz… - Nuclear Physics B, 1995 - Elsevier
We report on high statistics measurements of neutrino energy spectra carried out at 15, 40
and 95 meters from a 2800 Megawatt reactor, using detection modules filled with 6 Li-loaded …
and 95 meters from a 2800 Megawatt reactor, using detection modules filled with 6 Li-loaded …
DELLY: structural variant discovery by integrated paired-end and split-read analysis
Motivation: The discovery of genomic structural variants (SVs) at high sensitivity and
specificity is an essential requirement for characterizing naturally occurring variation and for …
specificity is an essential requirement for characterizing naturally occurring variation and for …
Mapping copy number variation by population-scale genome sequencing
Genomic structural variants (SVs) are abundant in humans, differing from other forms of
variation in extent, origin and functional impact. Despite progress in SV characterization, the …
variation in extent, origin and functional impact. Despite progress in SV characterization, the …