User profiles for Aalt Bast

A. Bast

Professor of Toxicology
Verified email at maastrichtuniversity.nl
Cited by 43975

Oxidants and antioxidants: state of the art

A Bast, GRMM Haenen, CJA Doelman - The American journal of medicine, 1991 - Elsevier
Reactive oxygen species are regarded as merely pernicious. This is incorrect for they play a
pivotal role in many physiologic reactions, such as cytochrome P450-mediated oxidations, …

Health effects of quercetin: from antioxidant to nutraceutical

AW Boots, GRMM Haenen, A Bast - European journal of pharmacology, 2008 - Elsevier
Quercetin, a member of the flavonoids family, is one of the most prominent dietary antioxidants.
It is ubiquitously present in foods including vegetables, fruit, tea and wine as well as …

Structural aspects of antioxidant activity of flavonoids

…, WP Van Bennekom, WJF Van Der Vijgh, A Bast - Free radical biology and …, 1996 - Elsevier
Flavonoids, a group of naturally occurring antioxidants and iron chelators, might be used as
cardioprotective agents in doxorubicin-induced cardiotoxicity, which is believed to be …

[HTML][HTML] Oxidative stress in chronic obstructive pulmonary disease

JE Repine, A Bast, IDA Lankhorst… - American journal of …, 1997 - atsjournals.org
COPD is an obstructive airway disorder characterized by a slowly progressive and irreversible
decrease in FEV1 (1, 2, 7). FEV1 decreases are caused by a narrowing of airway lumen …

The pharmacology of the antioxidant lipoic acid

GP Biewenga, GRMM Haenen, A Bast - General Pharmacology: The …, 1997 - Elsevier
1. Lipoic acid is an example of an existing drug whose therapeutic effect has been related to
its antioxidant activity. 2. 2. Antioxidant activity is a relative concept: it depends on the kind …

Applicability of an improved Trolox equivalent antioxidant capacity (TEAC) assay for evaluation of antioxidant capacity measurements of mixtures

…, GRMM Haenen, H van den Berg, A Bast - Food chemistry, 1999 - Elsevier
The TEAC (Trolox equivalent antioxidant capacity) assay is based on scavenging of 2,2′-azinobis-(3-
ethylbenzothiazoline-6-sulfonate) radical anions (ABTS − ). In this report we …

Increased exhalation of hydrogen peroxide in patients with stable and unstable chronic obstructive pulmonary disease.

…, PL Wielders, CL Van Herwaarden, A Bast - American journal of …, 1996 - atsjournals.org
An imbalance between oxidative stress and antioxidative capacity is thought to play an
important role in the development and progression of chronic obstructive pulmonary disease (…

A quantum chemical explanation of the antioxidant activity of flavonoids

…, WJF van der Vijgh, A Bast - Chemical research in …, 1996 - ACS Publications
Flavonoids are a group of naturally occurring antioxidants, which over the past years have
gained tremendous interest because of their possible therapeutic applicability. The …

Interactions between flavonoids and proteins: effect on the total antioxidant capacity

…, CGM Heijnen, HP Voss, A Bast - Journal of agricultural …, 2002 - ACS Publications
Flavonoids are potent antioxidants. It is also known that flavonoids bind to proteins. The
effect of the interaction between tea flavonoids and proteins on the antioxidant capacity was …

Flavonoids as scavengers of nitric oxide radical

…, GRMM Haenen, WJF Vandervijgh, A Bast - Biochemical and …, 1995 - Elsevier
Flavonoids are a group of naturally occurring compounds used, eg, in the treatment of vascular
endothelial damage. They are known to be excellent scavengers of oxygen free radicals. …