[HTML][HTML] Coenzyme Q10 dose-escalation study in hemodialysis patients: safety, tolerability, and effect on oxidative stress
CK Yeung, FT Billings, AJ Claessens, B Roshanravan… - BMC nephrology, 2015 - Springer
Background Coenzyme Q 10 (CoQ 10 ) supplementation improves mitochondrial coupling
of respiration to oxidative phosphorylation, decreases superoxide production in endothelial …
of respiration to oxidative phosphorylation, decreases superoxide production in endothelial …
CYP2D6 mediates 4-hydroxylation of clonidine in vitro: implication for pregnancy-induced changes in clonidine clearance
AJ Claessens, LJ Risler, S Eyal, DD Shen… - Drug Metabolism and …, 2010 - ASPET
Clonidine is a centrally acting, α-2 adrenergic agonist used for the treatment of hypertension
during pregnancy. The metabolic pathways of clonidine are poorly understood, and the …
during pregnancy. The metabolic pathways of clonidine are poorly understood, and the …
Potential contribution of cytochrome P450 2B6 to hepatic 4-hydroxycyclophosphamide formation in vitro and in vivo
BS Raccor, AJ Claessens, JC Dinh, JR Park… - Drug Metabolism and …, 2012 - ASPET
Results from retrospective studies on the relationship between cytochrome P450 (P450)
2B6 (CYP2B6) genotype and cyclophosphamide (CY) efficacy and toxicity in adult cancer …
2B6 (CYP2B6) genotype and cyclophosphamide (CY) efficacy and toxicity in adult cancer …
Rapid and sensitive analysis of reduced and oxidized coenzyme Q10 in human plasma by ultra performance liquid chromatography-tandem mass spectrometry and …
AJ Claessens, CK Yeung, LJ Risler… - Annals of clinical …, 2016 - journals.sagepub.com
Background Coenzyme Q10 is an endogenous antioxidant as well as a popular dietary
supplement. In blood circulation, coenzyme Q10 exists predominantly as its reduced ubiquinol-…
supplement. In blood circulation, coenzyme Q10 exists predominantly as its reduced ubiquinol-…
Sarcopenia and its relationship with bone mineral density in middle-aged and elderly European men
…, FC Wu, P Szulc, M Laurent, F Claessens… - Osteoporosis …, 2013 - Springer
The aim of this study was to determine the relationship between reduced muscle mass (sarcopenia)
and areal bone mineral density (BMD a ) in middle-aged and elderly community-…
and areal bone mineral density (BMD a ) in middle-aged and elderly community-…
Bidentate silane stationary phases for reversed-phase high-performance liquid chromatography
…, JB Adams, MA Van Straten, HA Claessens - Analytical …, 1998 - ACS Publications
… Claessens. The analysis of thiamin and its derivatives in whole blood samples under
high pH conditions of the mobile phase. Journal of Chromatography B 2005, 822 (1-2) , 316-321. …
high pH conditions of the mobile phase. Journal of Chromatography B 2005, 822 (1-2) , 316-321. …
Endocrine determinants of incident sarcopenia in middle‐aged and elderly European men
…, FC Wu, MR Laurent, F Claessens… - Journal of cachexia …, 2015 - Wiley Online Library
Background In men, the long‐term consequences of low serum levels of sex steroids, vitamin
D metabolites, and insulin‐like growth factor 1 (IGF‐1) on the evolution of muscle mass, …
D metabolites, and insulin‐like growth factor 1 (IGF‐1) on the evolution of muscle mass, …
Active vitamin D (1, 25-dihydroxyvitamin D) and bone health in middle-aged and elderly men: the European Male Aging Study (EMAS)
…, M Laurent, F Claessens, JE Adams… - The Journal of …, 2013 - academic.oup.com
Context: There is little information on the potential impact of serum 1,25-dihydroxyvitamin D [1,25(OH)
2 D] on bone health including turnover. Objective: The objective of the study was …
2 D] on bone health including turnover. Objective: The objective of the study was …
Lower bone turnover and relative bone deficits in men with metabolic syndrome: a matter of insulin sensitivity? The European Male Ageing Study
We examined cross-sectional associations of metabolic syndrome and its components with
male bone turnover, density and structure. Greater bone mass in men with metabolic …
male bone turnover, density and structure. Greater bone mass in men with metabolic …
Influence of bone remodelling rate on quantitative ultrasound parameters at the calcaneus and DXA BMDa of the hip and spine in middle-aged and elderly European …
…, S Verschueren, F Claessens, JE Adams… - European journal of …, 2011 - academic.oup.com
Objective To assess the influence of sex hormones on markers of bone turnover and to
explore the association between these markers and bone health in middle-aged and elderly …
explore the association between these markers and bone health in middle-aged and elderly …