The primary focus of chemoprevention research is the prevention of cancer using pharmacological,
biological, and nutritional interventions. Chemotherapeutic approaches that have …

Nrf2 is the key transcription factor regulating the antioxidant response. Nrf2 signaling is
repressed by Keap1 at basal condition and induced by oxidative stress. Keap1 is recently …

… time to achieve maximal nuclear accumulation (t 1/2 ). The Amax values were positively
correlated with SFN concentrations. The … Kong's laboratory for their contribution and comment. …

… Due to their low affinity for α-T transfer protein, hepatic γ-T and δ-T are less efficiently
transferred to very low-density lipoproteins. Therefore, smaller portions of γ-T and δ-T are found in …

… Despite high intake of γ-T, plasma concentrations of γ-T are about 10 times lower than that
of α-T. The reason for the plasma preference for α-T is in its specific selection by α-T transfer …

Inflammatory bowel diseases, chronic inflammatory disorders, have been strongly linked
with an increased risk of the development of colorectal cancer. Understanding the etiology of …

Abstract Development of cancer is a long-term and multistep process which comprises
initiation, progression, and promotion stages of carcinogenesis. Conceivably, it can be targeted …

The nuclear factor-erythroid 2-related factor 2 (Nrf2) plays a critical role in protecting various
tissues against inflammation, which is a potential risk factor for colorectal and other cancers. …

Sulforaphane (SFN) is a natural isothiocyanate that is present in cruciferous vegetables such
as broccoli and cabbage. Previous studies have shown that SFN is effective in preventing …

… One large study in Hong Kong involving 80 patients with SARS-CoV supported early
administration of antibodies for optimal clinical effect compared to later administration [145]. Limited …