Increased levels of the FoxM1 transcription factor accelerate development and progression of prostate carcinomas in both TRAMP and LADY transgenic mice
…, ML Major, CJ Detrisac, VV Kalinichenko, A Lyubimov… - Cancer research, 2006 - AACR
The proliferation-specific Forkhead Box M1 (FoxM1 or FoxM1b) transcription factor is
overexpressed in a number of aggressive human carcinomas. Mouse hepatocytes deficient in …
overexpressed in a number of aggressive human carcinomas. Mouse hepatocytes deficient in …
[HTML][HTML] Pharmacokinetics of cannabidiol, cannabidiolic acid, Δ9-tetrahydrocannabinol, tetrahydrocannabinolic acid and related metabolites in canine serum after …
…, BN Talsma, S Cital, A Lyubimov… - Frontiers in veterinary …, 2020 - frontiersin.org
Cannabidiol (CBD)-rich hemp extract use is increasing in veterinary medicine with little
examination of serum cannabinoids. Many products contain small amounts of Δ9-…
examination of serum cannabinoids. Many products contain small amounts of Δ9-…
A Novel l-Asparaginase with low l-Glutaminase Coactivity Is Highly Efficacious against Both T- and B-cell Acute Lymphoblastic Leukemias In Vivo
…, S Goossens, MJ Schlicht, KK Kabirov, AV Lyubimov… - Cancer research, 2018 - AACR
Acute lymphoblastic leukemia (ALL) is the most common type of pediatric cancer, although
about 4 of every 10 cases occur in adults. The enzyme drug l-asparaginase serves as a …
about 4 of every 10 cases occur in adults. The enzyme drug l-asparaginase serves as a …
Plasma pharmacokinetics, oral bioavailability, and interspecies scaling of the DNA methyltransferase inhibitor, zebularine
…, JL Eiseman, JM Covey, ER Glaze, AV Lyubimov… - Clinical cancer …, 2005 - AACR
Purpose: Zebularine is a DNA methyltransferase inhibitor proposed for clinical evaluation.
Experimental Design: We developed a liquid chromatography/mass spectrometry assay and …
Experimental Design: We developed a liquid chromatography/mass spectrometry assay and …
Blockade of a laminin-411–notch axis with CRISPR/Cas9 or a nanobioconjugate inhibits glioblastoma growth through tumor-microenvironment cross-talk
…, A Rekechenetskiy, V Falahatian, AV Lyubimov… - Cancer research, 2019 - AACR
… Alexander V. Lyubimov … Falahatian, AV Lyubimov, YL Chen, AV Ljubimov, JY Ljubimova …
Immunologic consequences of multiple, high-dose administration of allogeneic mesenchymal stem cells to baboons
KJ Beggs, A Lyubimov, JN Borneman… - Cell …, 2006 - journals.sagepub.com
Mesenchymal stem cells (MSCs) express low immunogenicity and demonstrate
immunomodulatory properties in vitro that may safely allow their transplantation into unrelated …
immunomodulatory properties in vitro that may safely allow their transplantation into unrelated …
Implantable chemotherapy‐loaded silk protein materials for neuroblastoma treatment
…, M Pilichowska, AV Lyubimov… - … journal of cancer, 2017 - Wiley Online Library
Neuroblastoma is the most common extracranial childhood solid tumor. Treatment of high
risk tumors require intense multicycle chemotherapies, resulting in short‐ and long‐term …
risk tumors require intense multicycle chemotherapies, resulting in short‐ and long‐term …
Genetic potential of milk productivity of black-and-white cows depending on selection and management
A Lyubimov, E Martynova, Y Isupova… - BIO Web of …, 2020 - bio-conferences.org
Currently an increasing attention is paid to breeding animals ensuring the greatest genetic
progress of populations in livestock productivity, ie stud bulls. Hence, the study of the …
progress of populations in livestock productivity, ie stud bulls. Hence, the study of the …
The effects of tetrathiomolybdate (TTM, NSC-714598) and copper supplementation on fertility and early embryonic development in rats
AV Lyubimov, JA Smith, SD Rousselle… - Reproductive …, 2004 - Elsevier
Based on its ability to chelate copper, TTM is being studied as an antiangiogenic agent for
cancer therapy. The purpose of this study was to evaluate the toxicity of TTM and the …
cancer therapy. The purpose of this study was to evaluate the toxicity of TTM and the …
Role for platelet glycoprotein Ib-IX and effects of its inhibition in endotoxemia-induced thrombosis, thrombocytopenia, and mortality
…, S Pavlovic, A Krbanjevic, AV Lyubimov… - … , and vascular biology, 2013 - Am Heart Assoc
Objective— Poor prognosis of sepsis is associated with bacterial lipopolysaccharide (LPS)-induced
intravascular inflammation, microvascular thrombosis, thrombocytopenia, and …
intravascular inflammation, microvascular thrombosis, thrombocytopenia, and …