7-Dehydrocholesterol is an endogenous suppressor of ferroptosis

…, SG Doll, EL Schaefer, I Ekpo, W Schmitz, A Horling… - Nature, 2024 - nature.com
Ferroptosis is a form of cell death that has received considerable attention not only as a means
to eradicate defined tumour entities but also because it provides unforeseen insights into …

7-Dehydrocholesterol is an endogenous suppressor of ferroptosis

…, D Pratt, M Fedorova, A Wehmann, A Horling… - 2021 - researchsquare.com
Ferroptosis is a form of cell death that has received considerable attention not only as a means
to eradicate defined tumour entities but also because it provides unforeseen insights into …

A new class of selective and potent 7-dehydrocholesterol reductase inhibitors

A Horling, C Müller, R Barthel… - Journal of Medicinal …, 2012 - ACS Publications
We prepared a number of N-phenethyltetrahydroisoquinolines structurally related to
protoberberines. They were tested for activity against bacteria, fungi, and human leukemia HL-60 …

Time-dependent inhibition of CYP2C19 by isoquinoline alkaloids: in vitro and in silico analysis

…, R Väänänen, P Imming, A Meyer, A Horling… - Drug metabolism and …, 2015 - ASPET
The cytochrome P450 2C19 (CYP2C19) enzyme plays an important role in the metabolism of
many commonly used drugs. Relatively little is known about CYP2C19 inhibitors, including …

[PDF][PDF] Potential metabolism-based drug interactions with isoquinoline alkaloids: an in vitro and in silico study

K Salminen - 2018 - erepo.uef.fi
… I also wish to thank Aline Horling Ph.D. for the provision of some isoquinoline alkaloids. … IV
Salminen KA, Rahnasto-Rilla M, Väänänen R, Imming P, Meyer A, Horling A, Poso A, Laitinen …

The influence of thermal annealing on residual stresses and mechanical properties of arc-evaporated TiCxN1− x (x= 0, 0.15 and 0.45) thin films

L Karlsson, A Hörling, MP Johansson, L Hultman… - Acta Materialia, 2002 - Elsevier
We report the stress relaxation behavior of arc-evaporated TiC x N 1− x thin films during
isothermal annealing between 350 and 900C. Films with x= 0, 0.15, and 0.45, each having an …

An investigation of the accuracy of Doppler broadened line profile analysis applied to plasma diagnostics

P Hörling, KD Zastrow - Journal of Quantitative Spectroscopy and Radiative …, 1995 - Elsevier
… The accuracy to which a line shape and its width can be determined depend on several …
One essential factor is the total number of counts in a line which can often not be controlled or …

Ion temperature, heating and scaling relations at the Extrap-T1 reversed-field pinch

P Hörling, G Hedin, JH Brzozowski… - Plasma physics and …, 1996 - iopscience.iop.org
Investigations of the temperatures of the in situ impurity ions,,, and have been performed at
the Extrap-T1 reversed-field pinch (RFP) via measurements of the Doppler broadening of …

Mallet finger–A modified technique using the finger nail as a fixation point for the temporary immobilization of the distal interphalangeal joint–A biomechanical study

P Schwendinger, L Horling, W Schmolz, R Hörmann… - Clinical …, 2019 - Elsevier
Background The aim of the current biomechanical study was to investigate a newly developed
surgical technique for mallet fingers. The new method is based on the Ishiguro method …

Quantitative Serial Imaging of an 124I Anti-CEA Monoclonal Antibody in Tumor-Bearing Mice

JR Bading, M Hörling, LE Williams… - Cancer biotherapy & …, 2008 - liebertpub.com
… Shown are the mean profiles (horizontal and vertical) of 10 consecutive transaxial image
slices (maximum a posteriori reconstruction) of a line source positioned approximately in the …