User profiles for Amalio Telenti

Amalio Telenti

The Scripps Research Institute
Verified email at scripps.edu
Cited by 70761

[HTML][HTML] Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody

…, RE Chen, C Havenar-Daughton, G Snell, A Telenti… - Nature, 2020 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a newly emerged
coronavirus that is responsible for the current pandemic of coronavirus disease 2019 (COVID-19), …

A primer on deep learning in genomics

…, A Abid, P Mohammadi, A Torkamani, A Telenti - Nature …, 2019 - nature.com
Deep learning methods are a class of machine learning techniques capable of identifying
highly complex patterns in large datasets. Here, we provide a perspective and primer on deep …

Detection of rifampicin-resistance mutations in Mycobacterium tuberculosis

A Telenti, P Imboden, F Marchesi, L Matter, K Schopfer… - The Lancet, 1993 - Elsevier
Control of tuberculosis is threatened by widespread emergence of drug resistance in
Mycobacterium tuberculosis. Understanding the molecular basis of resistance might lead to …

Rapid identification of mycobacteria to the species level by polymerase chain reaction and restriction enzyme analysis

A Telenti, F Marchesi, M Balz, F Bally… - Journal of clinical …, 1993 - Am Soc Microbiol
A method for the rapid identification of mycobacteria to the species level was developed on
the basis of evaluation by the polymerase chain reaction (PCR) of the gene encoding for the …

A whole-genome association study of major determinants for host control of HIV-1

…, NL Letvin, AJ McMichael, BF Haynes, A Telenti… - science, 2007 - science.org
Understanding why some people establish and maintain effective control of HIV-1 and
others do not is a priority in the effort to develop new treatments for HIV/AIDS. Using a whole-…

Genetic variation in IL28B is associated with chronic hepatitis C and treatment failure: a genome-wide association study

…, T Berg, S Bergmann, F Negro, A Telenti… - Gastroenterology, 2010 - Elsevier
BACKGROUND & AIMS: Hepatitis C virus (HCV) induces chronic infection in 50% to 80% of
infected persons; approximately 50% of these do not respond to therapy. We performed a …

SARS-CoV-2 immune evasion by the B. 1.427/B. 1.429 variant of concern

…, WC Van Voorhis, LE Rosen, G Snell, A Telenti… - Science, 2021 - science.org
A novel variant of concern (VOC) named CAL.20C (B.1.427/B.1.429), which was originally
detected in California, carries spike glycoprotein mutations S13I in the signal peptide, W152C …

[HTML][HTML] SARS-CoV-2 RBD antibodies that maximize breadth and resistance to escape

…, L Piccoli, F Benigni, J Neyts, A Telenti… - Nature, 2021 - nature.com
An ideal therapeutic anti-SARS-CoV-2 antibody would resist viral escape 1 , 2 – 3 , have
activity against diverse sarbecoviruses 4 , 5 , 6 – 7 , and be highly protective through viral …

Antiretroviral treatment of adult HIV infection: 2010 recommendations of the International AIDS Society–USA panel

…, P Cahn, JSG Montaner, G Rizzardini, A Telenti… - Jama, 2010 - jamanetwork.com
Context Recent data regarding the consequences of untreated human immunodeficiency
virus (HIV) infection and the expansion of treatment choices for antiretroviral-naive and …

Antiretroviral treatment of adult HIV infection: 2012 recommendations of the International Antiviral Society–USA panel

MA Thompson, JA Aberg, JF Hoy, A Telenti, C Benson… - Jama, 2012 - jamanetwork.com
Context New trial data and drug regimens that have become available in the last 2 years
warrant an update to guidelines for antiretroviral therapy (ART) in human immunodeficiency …