Purpose: Oxaliplatin displays a frequent dose-limiting neurotoxicity due to its interference
with neuron voltage-gated sodium channels through one of its metabolites, oxalate, a calcium …

This article deals with the fate of oxaliplatin 1 and 3 h after its iv administration (130 mg/m 2
) to three patients. Its binding to plasma proteins and penetration into red blood cells were …

A high-performance liquid chromatography coupled with electrospray tandem mass spectrometry
(LC/MS/MS) procedure for the simultaneous determination of diazepam from avizafone…

Despite pituitary hormone replacement, patients with craniopharyngioma often complain of
fatigue. They may have deficient control of catecholamine secretion caused by hypothalamic …

Aims/Methods: Our aim was to the antifibrotic and hemodynamic effects of simvastatin (SMV),
pentoxifylline (PTX) and spironolactone (SPN), three drugs which may have antifibrotic and/…

Importance The DRAMES (Décès en Relation avec l’Abus de Médicaments Et de Substances)
register is a database of drug-related deaths with the aim of identifying the psychoactive …

Background Diet-induced weight reduction promotes a decrease in resting energy expenditure
that could partly explain the difficulty in maintaining reduced body mass. Whether this …

Suicide by stabbing to the head and/or driving sharp objects into the skull is of extreme rarity.
This article reports the case of a 27-year-old man, who committed suicide by multiple knife …

Purpose To explore feasibility, maximum-tolerated dose (MTD), and recommended dose (RD)
for phase II studies of weekly oxaliplatin for the treatment of relapsed or refractory …

Actual and simulated microgravity induces hypovolemia and cardiovascular deconditioning,
associated with vascular dysfunction. We hypothesized that vasoconstriction of skin …