Background Stem-cell-based, tissue engineered transplants might offer new therapeutic options
for patients, including children, with failing organs. The reported replacement of an adult …

Dermal skin‐derived fibroblasts from rodent and human have been found to exhibit mesenchymal
surface antigen immunophenotype and differentiation potential along the three main …

Damage to and degeneration of articular cartilage is a major health issue in industrialized
nations. Articular cartilage has a particularly limited capacity for auto regeneration. At present, …

Primary hepatocytes represent a well-accepted in vitro cell culture system for studies of drug
metabolism, enzyme induction, transplantation, viral hepatitis, and hepatocyte regeneration. …

Objective: Tissue engineering of heart valves represents a new experimental concept to
improve current modes of therapy in valvular heart disease. Drawbacks of glutaraldehyde fixed …

Background—Tissue engineering using in vitro–cultivated autologous vascular wall cells is
a new approach to biological heart valve replacement. In the present study, we analyzed a …

Moving towards in situ tracheal regeneration: the bionic tissue engineered transplantation
approach - Bader - 2010 - Journal of Cellular and Molecular Medicine - Wiley Online Library …

Cultures of primary hepatocytes and hepatoma cell line HepG2 are frequently used in in vitro
models for human biotransformation studies. In this study, we characterized and compared …

Isolated hepatocytes in spheroid configuration exhibit a high degree of cell–cell contacts,
which are important in the maintenance of viability and liver specific functions. In the absence …

The small intestinal metabolism of tacrolimus, which is used as an immunosuppressant in
transplantation medicine, was investigated in this study. Tacrolimus was metabolized in vitro …