User profiles for B Burchell
Professor Brendan BurchellProfessor of the Social Sciences, University of Cambridge Verified email at cam.ac.uk Cited by 7490 |
The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence
PI Mackenzie, IS Owens, B Burchell… - Pharmacogenetics …, 1997 - journals.lww.com
This review represents an update of the nomenclature system for the UDP glucuronosyltransferase
gene superfamily, which is based on divergent evolution. Since the previous review …
gene superfamily, which is based on divergent evolution. Since the previous review …
Nomenclature update for the mammalian UDP glycosyltransferase (UGT) gene superfamily
PI Mackenzie, KW Bock, B Burchell… - Pharmacogenetics …, 2005 - journals.lww.com
Several novel UDP glycosyltransferase (UGT) genes, mainly UDP glucuronosyltransferases,
have been identified in the human, mouse and rat genomes and in other mammalian …
have been identified in the human, mouse and rat genomes and in other mammalian …
UDP-glucuronosyltransferases
B Burchell, MWH Coughtrie - Pharmacology & therapeutics, 1989 - Elsevier
The pharmacological and toxicological importance of UDP-glucuronosyltransferases (UDPGTs;
EC 2.4. 1.17) has been emphasized previously by Dutton in comprehensive and wide-…
EC 2.4. 1.17) has been emphasized previously by Dutton in comprehensive and wide-…
[BOOK][B] Job insecurity and work intensification
B Burchell, D Ladipo, F Wilkinson - 2002 - api.taylorfrancis.com
… Brendan Burchell and Frank Wilkinson raised the funds for the project and steered it through
the initial planning stages. Maria Hudson, David Ladipo and Hannah Reed were appointed …
the initial planning stages. Maria Hudson, David Ladipo and Hannah Reed were appointed …
[HTML][HTML] Genetic variation in bilirubin UDP-glucuronosyltransferase gene promoter and Gilbert's syndrome
G Monaghan, M Ryan, R Hume, B Burchell, R Seddon - The Lancet, 1996 - thelancet.com
Background The genetic basis of Gilbert's syndrome is ill-defined. This common mild
hyperbilirubinaemia sometimes presents as an intermittent jaundice. A reduced hepatic bilirubin …
hyperbilirubinaemia sometimes presents as an intermittent jaundice. A reduced hepatic bilirubin …
[HTML][HTML] The multidrug resistance protein 5 functions as an ATP-dependent export pump for cyclic nucleotides
G Jedlitschky, B Burchell, D Keppler - Journal of Biological Chemistry, 2000 - ASBMB
… B, immunoblot analysis of MRP5 in crude membrane fractions (100,000 × g Pellets) and
purified plasma membrane vesicles (Membranes) prepared from V79-MRP5 and control cells (…
purified plasma membrane vesicles (Membranes) prepared from V79-MRP5 and control cells (…
The quality of employment and decent work: definitions, methodologies, and ongoing debates
This article explores the development of concepts related to the ‘quality of employment’ in the
academic literature in terms of their definition, methodological progress and ongoing policy …
academic literature in terms of their definition, methodological progress and ongoing policy …
UDP-glucuronosyltransferases: a family of detoxifying enzymes
TR Tephly, B Burchell - Trends in Pharmacological Sciences, 1990 - cell.com
… , reviewed here by Thomas Tephly and Brian Burchell, have given new insight into the …
Robertson and B. Burchell, unpublished) and it is likely that these two different UDPGTs are …
Robertson and B. Burchell, unpublished) and it is likely that these two different UDPGTs are …
In vitro analysis of human drug glucuronidation and prediction of in vivo metabolic clearance
MG Soars, B Burchell, RJ Riley - Journal of Pharmacology and Experimental …, 2002 - ASPET
The glucuronidation of a number of commonly used hepatic uridine diphosphate
glucuronosyltransferase drug substrates has been studied in human tissue microsomes. Prediction …
glucuronosyltransferase drug substrates has been studied in human tissue microsomes. Prediction …
ATP-dependent transport of bilirubin glucuronides by the multidrug resistance protein MRP1 and its hepatocyte canalicular isoform MRP2
…, J HUMMEL-EISENBEISS, B BURCHELL… - Biochemical …, 1997 - portlandpress.com
Bilirubin is secreted from the liver into bile mainly as monoglucuronosyl and bisglucuronosyl
conjugates. We demonstrate for the first time that ATP-dependent transport of both bilirubin …
conjugates. We demonstrate for the first time that ATP-dependent transport of both bilirubin …