LC–MS of oligonucleotides: applications in biomedical research

B Basiri, MG Bartlett - Bioanalysis, 2014 - Future Science
Recent findings have elucidated numerous novel biological functions for oligonucleotides.
Current standard methods for the study of oligonucleotides (ie, hybridization and PCR) are …

The role of fluorinated alcohols as mobile phase modifiers for LC-MS analysis of oligonucleotides

B Basiri, H van Hattum, WD van Dongen… - Journal of the …, 2016 - ACS Publications
… For DMCHA/HFIP mobile phase, a gradient from 20% to 25% B in 6 min was used during
UPLC separation. In the case of DMCHA/HFMIP, the gradient was 12%–17%, respectively. …

[HTML][HTML] The effect of kangaroo mother care on physiological parameters of premature infants in Hamadan City, Iran

P Parsa, S Karimi, B Basiri… - The Pan African Medical …, 2018 - ncbi.nlm.nih.gov
… In the present study, the duration of kangaroo care was not considered, the results for
oxygen saturation were in line with a Basiri study. It is suggested that, the positive effects of …

[HTML][HTML] Metabolite profiling of the antisense oligonucleotide eluforsen using liquid chromatography-mass spectrometry

J Kim, B Basiri, C Hassan, C Punt… - … Therapy-Nucleic Acids, 2019 - cell.com
Eluforsen (previously known as QR-010) is a 33-mer 2′-O-methyl modified phosphorothioate
antisense oligonucleotide targeting the F508del mutation in the gene encoding CFTR …

[HTML][HTML] Application of locked nucleic acid oligonucleotides for siRNA preclinical bioanalytics

MB Thayer, JM Lade, D Doherty, F Xie, B Basiri… - Scientific Reports, 2019 - nature.com
… % B for the initial 0.5 minutes, followed by a linear gradient to 50% B at 9.5 minutes, then
another linear gradient to 95% B … ; and then ramped down to 2% B at 13 minutes and kept at 2% …

[HTML][HTML] The etiology, clinical type, and short outcome of seizures in newbornshospitalized in Besat Hospital/Hamadan/Iran

MK Sabzehei, B Basiri… - Iranian journal of child …, 2014 - ncbi.nlm.nih.gov
… Mohammad Kazem SABZEHEI, MD , 1 Behnaz BASIRI, MD , 1 and Hassan BAZMAMOUN,
MD 1 … b) Clonic seizure: when the neonate had rhythmic, repetitive shaking of isolated parts …

[HTML][HTML] Neonatal mortality and its main determinants in premature infants hospitalized in neonatal intensive care unit in Fatemieh Hospital, Hamadan, Iran

B Basiri, FE Ashari, M Shokouhi… - Journal of …, 2015 - brieflands.com
Background: Neonatal mortality is one of the main indicators of health and welfare of population.
Prematurity is one of the most important causes of neonatal mortality. We determined …

Assessing the interplay between the physicochemical parameters of ion-pairing reagents and the analyte sequence on the electrospray desorption process for …

B Basiri, MM Murph, MG Bartlett - Journal of The American …, 2017 - ACS Publications
Alkylamines are widely used as ion-pairing agents during LC-MS of oligonucleotides. In
addition to a better chromatographic separation, they also assist with the desorption of …

Direct identification of microribonucleic acid miR-451 from plasma using liquid chromatography mass spectrometry

B Basiri, JM Sutton, S Hooshfar, CC Byrnes… - … of Chromatography A, 2019 - Elsevier
In recent years, small endogenous RNAs have come to the forefront of both basic and
translational research. For example, many studies have pointed to the potential role of microRNAs …

[HTML][HTML] The frequency of intraventricular hemorrhage and its risk factors in premature neonates in a hospital's NICU

B Basiri, MK Sabzehei, MS Solgi… - Iranian journal of …, 2021 - ncbi.nlm.nih.gov
Objective Intra-ventricular hemorrhage (IVH) is the leading cause of mortality and disability
in premature neonates. The present study aimed to determine the frequency of IVH and its …