User profiles for B. Ludewig

Burkhard Ludewig

Professor, Head Medical Research Center, Kantonsspital St. Gallen, Switzerland
Verified email at kssg.ch
Cited by 19245

Fibroblasts as immune regulators in infection, inflammation and cancer

…, M Coles, T Thomas, G Kollias, B Ludewig… - Nature Reviews …, 2021 - nature.com
… This includes FRC-generated chemokine gradients to localize proliferating B cells to the T
cell–B cell border, thereby causing stretching of the B cell-interacting reticular cell network to …

Form follows function: lymphoid tissue microarchitecture in antimicrobial immune defence

T Junt, E Scandella, B Ludewig - Nature Reviews Immunology, 2008 - nature.com
… 1a), SLOs consist of three zones: an outer antigen-sampling zone, which is an APC-rich
area that binds and delivers antigen to the B- and T-cell zones; the B-cell activation zone (B-cell …

[HTML][HTML] Ribose 2′-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5

…, W Barchet, MS Diamond, SG Siddell, B Ludewig… - Nature …, 2011 - nature.com
… (b) ClustalW2 alignment of coronavirus nsp16 amino acid sequences, representative of α-,
β- and γ-coronaviruses. Keys (bottom right) identify sequence conservation (amino acid …

Guidelines for the use of flow cytometry and cell sorting in immunological studies*

…, A Lovett‐Racke, E Lubberts, B Ludewig… - European journal of …, 2017 - Wiley Online Library
From a technical point of view a flow cytometer is a light detection device capable of detecting
photons of different wavelengths over a high dynamic range. In order to achieve a high …

Fibroblastic reticular cells at the nexus of innate and adaptive immune responses

…, C Gil‐Cruz, B Ludewig - Immunological …, 2019 - Wiley Online Library
… antigen on their surface to B cells using a broad … B cells in the germinal center reaction.42
FDC and probably other FRC subsets43 in the B-cell follicle control the survival of B cells via B

Immune surveillance against a solid tumor fails because of immunological ignorance

…, P Klenerman, U Karrer, B Ludewig… - Proceedings of the …, 1999 - National Acad Sciences
… D b -GP33–41 expression (not shown). … b ) mice treated with the same repetitive injection
protocol were challenged with 20 μg of DNP coupled to P13 [helper epitope GP60–80 in H-2 b (…

Restoration of lymphoid organ integrity through the interaction of lymphoid tissue–inducer cells with stroma of the T cell zone

…, D Finke, SA Luther, T Junt, B Ludewig - Nature …, 2008 - nature.com
B cell responses after day 8 of LCMV infection was not due to lack of sufficient B cells, because
adoptive transfer of B … 8) did not enhance the B cell response to the secondary antigen …

Control of coronavirus infection through plasmacytoid dendritic-cell–derived type I interferon

…, M Spiegel, KS Lang, S Akira, V Thiel, B Ludewig - Blood, 2007 - ashpublications.org
… Purity of both cell preparation was for all donors more than 90% (with B cells being the …
rising liver enzyme values in serum (Figure 3B) and an acute hemorrhagic liver disease with …

Dendritic cells induce autoimmune diabetes and maintain disease via de novo formation of local lymphoid tissue

B Ludewig, B Odermatt, S Landmann… - The Journal of …, 1998 - rupress.org
… Bone marrow cells were depleted of lymphocytes, B cells, and IA b positive cells using a
cocktail of mAbs (YTS191.1, YTS169.4.2, RA3-3A1/6.1, B21-2) and goat anti–rat IgG–coated …

Aggravation of viral hepatitis by platelet-derived serotonin

…, B Ludewig, T Calzascia, B Bolinger… - Nature medicine, 2008 - nature.com
… More than 500 million people worldwide are persistently infected with hepatitis B virus or
hepatitis C virus 1 . Although … We purchased monoclonal antibody to granzyme B from Caltag. …