User profiles for C Sengstag

Christian Sengstag

Stabsstelle Forschung, Vizerektorat Forschung, Universität Basel
Verified email at unibas.ch
Cited by 1920

The role of mitotic recombination in carcinogenesis

C Sengstag - Critical reviews in toxicology, 1994 - Taylor & Francis
… The c-myc protooncogene also has been observed to be translocated to the C a-region
of the T-cell receptor-a in translocation [t(8; 14)(q24;ql l)].” The exact molecular process that …

Metabolism of promutagens catalyzed by Drosophila melanogaster CYP6A2 enzyme in Saccharomyces cerevisiae

…, B Weibel, FE Würgler, C Sengstag - Environmental and …, 1996 - Wiley Online Library
… isogenic yeast strain can be used as control [Sengstag and Wurgler, 19941. In this study we
… 50C for at least 24 hr, followed by two washes for 15 min at 50C in 6 X SSC and 0.1% SDS. …

Caffeine, estradiol, and progesterone interact with human CYP1A1 and CYP1A2. Evidence from cDNA-directed expression in Saccharomyces cerevisiae.

…, M Probst, FE Würgler, C Sengstag - Drug metabolism and …, 1993 - ASPET
Heterologous expression of cytochrome P-450 cDNAs in yeast is a potent instrument for the
study of enzyme-specific parameters and can be used to answer questions with regard to …

Genotoxicity of ethyl carbamate (urethane) in Salmonella, yeast and human lymphoblastoid cells

P Hübner, PM Groux, B Weibel, C Sengstag… - … /Genetic Toxicology and …, 1997 - Elsevier
C, molten top agar was added and the mixture was poured on minimal plates. The plates were
incubated for 48 h at 37C … were then incubated for 4 h at 30C on a shaker. The cells were …

[HTML][HTML] The Next Generation Scientist program: capacity-building for future scientific leaders in low-and middle-income countries

…, F Mirza, C Sengstag, C Masimirembwa… - BMC Medical …, 2018 - Springer
Background Scientific and professional development opportunities for early career scientists
in low- and middle- income countries (LMICs) are limited and not consistent. There is a …

The sequence of the Saccharomyces cerevisiae gene PH02 codes for a regulatory protein with unusual aminoacid composition

C Sengstag, A Hinnen - Nucleic acids research, 1987 - academic.oup.com
A new centromere vector for the construction of a Saccharomyces cerevisiae gene library,
allowing direct selection for DNA insert, will be described. From that library the gene for the …

Genetic and biochemical evaluation of eucaryotic membrane protein topology: multiple transmembrane domains of Saccharomyces cerevisiae 3-hydroxy-3 …

C Sengstag, C Stirling, R Schekman… - Molecular and Cellular …, 1990 - Am Soc Microbiol
… Sequence comparisons of the two isozymes reveals that they are very similar in their C-terminaldomains,
which harbor the catalytic activity of the enzyme (4). Less conservation is ob…

Genotoxicity of Aflatoxin B1: Evidence for a Recombination-mediated Mechanism in Saccharomyces cerevisiae

C Sengstag, B Weibel, M Fasullo - Cancer research, 1996 - AACR
The potent liver carcinogen aflatoxin B 1 (AFB1) is metabolized by cytochrome P450 to the
mutagenic epoxide. We have observed that activated AFB1 also strongly induced mitotic …

Postnatal ontogeny of hippocampal expression of the mineralocorticoid and glucocorticoid receptors in the common marmoset monkey

…, I Knuesel, T Oertle, C Sengstag… - European Journal of …, 2005 - Wiley Online Library
… After an initial denaturation step at 95 C for 5 min, 35 cycles were run including 95 C for
30 s, 50 C for 30 s and 72 C for 1 min. A final extension step comprised 72 C for 10 min. One-half …

Liver carcinogen aflatoxin B1 as an inducer of mitotic recombination in a human cell line

PM Stettler, C Sengstag - … in cooperation with the University of …, 2001 - Wiley Online Library
C, followed by 32 cycles for 30 s at 95C, 50 s at 62C, and 1 min at 72C and then by a final
elongation for 7 min at 72C… Amplification products were either directly used or stored at −20C. …