The pharmacokinetics of intravenously administered cefepime (1000 mg over 30 minutes)
were studied in 5 healthy volunteers and 20 patients with various degrees of renal impairment…

The pharmacokinetics of cefepime in 31 young, healthy volunteers were assessed after the
administration of single and multiple 250-, 500-, 1,000-, or 2,000-mg intravenous doses. …

In this double-blind, single-dose phase I study, the safety and tolerance of cefepime were
assessed in 24 healthy male subjects, with ceftazidime as the control drug. Four subjects in …

The effect of food on the pharmacokinetics of didanosine was evaluated in an open two‐way
crossover study in eight male subjects who tested seropositive for the human …

Steady state pharmacokinetics, absolute bioavailability, and dose proportionality of cefepime
were evaluated in healthy male subjects after single (250, 500, 1000, or 2000 mg) and …

The effects of age and gender on the pharmacokinetics of cefepime were examined in 48
volunteers following administration of a single 1,000-mg intravenous dose. Male and female …

The evaluation and development of didanosine as a therapy for HIV-infection has demonstrated
that results of cell-culture studies are only approximate predictors of clinical effects. …

The pharmacokinetics of didanosine (2',3'‐dideoxyinosine) after intravenous and oral
administration were evaluated in an open, escalating‐dose phase I study in patients with acquired …

The pharmacokinetics of cefepime were studied in 10 male patients receiving continuous
ambulatory peritoneal dialysis therapy. Five patients received a single 1,000-mg dose and the …

The pharmacokinetics of didanosine and ciprofloxacin were evaluated following the
administration of multiple oral doses of each drug as a single agent or in combination. Didanosine …