Carcinogenic nitrosamines: free radical aspects of their action

H Bartsch, E Hietanen, C Malaveille - Free radical Biology and medicine, 1989 - Elsevier
… to form c~-hydroxynitrosamines or decompose into nitric oxide and N-methylformaldimine.
In the presence of phosphate, mutagenic ot-phosphonooxy derivatives are formed from …

Validation and comparative studies on 180 chemicals with S. typhimurium strains and V79 Chinese hamster cells in the presence of various metabolizing systems

H Bartsch, C Malaveille, AM Camus… - … Research/Reviews in …, 1980 - Elsevier
Results from tests on a total of 180 compounds in the Salmonella/microsome assay and its
adapted procedures are summarized. The following specific problems were analyzed: the …

Does increased endogenous formation of N-nitroso compounds in the human colon explain the association between red meat and colon cancer?

…, B Pignatelli, JRA Pollock, A Ellul, C Malaveille… - …, 1996 - academic.oup.com
High red meat diets have been linked with risk of sporadic colorectal cancer, but their effects
on mutations which occur in this cancer are unknown. G→A transitions in K-ras occur in …

Environmental tobacco smoke and risk of respiratory cancer and chronic obstructive pulmonary disease in former smokers and never smokers in the EPIC prospective …

…, S Garte, E Gormally, P Hainaut, C Malaveille… - Bmj, 2005 - bmj.com
Objectives To investigate the association between environmental tobacco smoke, plasma
cotinine concentration, and respiratory cancer or death. Design Nested case-control study …

DNA repair polymorphisms and cancer risk in non-smokers in a cohort study

…, S Polidoro, S Garte, H Autrup, C Malaveille… - …, 2006 - academic.oup.com
Environmental carcinogens contained in air pollution, such as polycyclic aromatic hydrocarbons,
aromatic amines or N -nitroso compounds, predominantly form DNA adducts but can …

Black (air-cured) and blond (flue-cured) tobacco cancer risk IV: molecular dosimetry studies implicate aromatic amines as bladder carcinogens

H Bartsch, C Malaveille, M Friesen, FF Kadlubar… - European Journal of …, 1993 - Elsevier
Tobacco smoking causes a major fraction of male urinary bladder cancers and the relative
risk of bladder cancer is reported to be two to three times higher for smoking of black (air-…

DNA repair gene polymorphisms, bulky DNA adducts in white blood cells and bladder cancer in a case‐control study

…, S Carturan, M Peluso, C Malaveille… - … Journal of Cancer, 2001 - Wiley Online Library
… step at 95C for 3 min; 35 cycles of PCR consisting of 95C for 20 sec, 20 sec at the appropriate
annealing temperature and 72C for 20 sec; then a final extension step at 72C for 5 min. …

Air pollution and risk of lung cancer in a prospective study in Europe

…, S Garte, P Hainaut, C Malaveille… - … journal of cancer, 2006 - Wiley Online Library
… Christian Malaveille… Metabolic polymorphisms have been investigated at IARC (C. Malaveille),
at the Aarhus University (H. Autrup) and at the Genetics Research Institute, Milan (S. Garte…

TP53 and KRAS2 Mutations in Plasma DNA of Healthy Subjects and Subsequent Cancer Occurrence: A Prospective Study

…, A Munnia, L Airoldi, H Autrup, C Malaveille… - Cancer research, 2006 - AACR
In cancer patients, plasma often contains mutant DNA released by cancer cells. We have
assessed the significance of plasma DNA mutations for subsequent cancer development in …

GST, NAT, SULT1A1, CYP1B1 genetic polymorphisms, interactions with environmental exposures and bladder cancer risk in a high‐risk population

…, P Boffetta, P Brennan, C Malaveille… - … Journal of Cancer, 2004 - Wiley Online Library
Tobacco smoking and occupation are major risk factors of bladder cancer via exposure to
polycyclic aromatic hydrocarbons (PAHs) and aromatic amines. Glutathione S‐transferase (…