User profiles for C. Vens
Celine Vensprofessor, Katholieke Universiteit Leuven Verified email at kuleuven.be Cited by 3407 |
Strategies to improve radiotherapy with targeted drugs
AC Begg, FA Stewart, C Vens - Nature Reviews Cancer, 2011 - nature.com
Radiotherapy is used to treat approximately 50% of all cancer patients, with varying success.
The dose of ionizing radiation that can be given to the tumour is determined by the …
The dose of ionizing radiation that can be given to the tumour is determined by the …
Decision trees for hierarchical multi-label classification
… To construct the tree for class c with such a learner, we label the class c examples positive
and all the other examples negative. The resulting tree predicts the probability that a new …
and all the other examples negative. The resulting tree predicts the probability that a new …
Predicting human olfactory perception from chemical features of odor molecules
It is still not possible to predict whether a given molecule will have a perceived odor or what
olfactory percept it will produce. We therefore organized the crowd-sourced DREAM …
olfactory percept it will produce. We therefore organized the crowd-sourced DREAM …
Tree ensembles for predicting structured outputs
In this paper, we address the task of learning models for predicting structured outputs. We
consider both global and local predictions of structured outputs, the former based on a single …
consider both global and local predictions of structured outputs, the former based on a single …
Ensembles of multi-objective decision trees
Ensemble methods are able to improve the predictive performance of many base classifiers.
Up till now, they have been applied to classifiers that predict a single target attribute. Given …
Up till now, they have been applied to classifiers that predict a single target attribute. Given …
[HTML][HTML] Predicting gene function using hierarchical multi-label decision tree ensembles
… We will first investigate if ensembles improve the predictive performance of CLUS-HMC
in gene function prediction and if so, quantify this difference. We will then compare …
in gene function prediction and if so, quantify this difference. We will then compare …
[HTML][HTML] Homologous Recombination Deficiency Scar: Mutations and Beyond—Implications for Precision Oncology
…, Y Cong, J Theys, A Van Hoeck, C Vens… - Cancers, 2022 - mdpi.com
Simple Summary A characteristic across several cancer types is a homologous recombination
deficiency (HRD). HRD is associated with a better response to several anticancer …
deficiency (HRD). HRD is associated with a better response to several anticancer …
Novel therapeutics in combination with radiotherapy to improve cancer treatment: rationale, mechanisms of action and clinical perspective
M Verheij, C Vens, B van Triest - Drug Resistance Updates, 2010 - Elsevier
Our increased understanding of the molecular processes underlying cellular sensitivity to
ionizing radiation has led to the identification of novel targets for intervention. New agents have …
ionizing radiation has led to the identification of novel targets for intervention. New agents have …
T cell activation responses are differentially regulated during clinorotation and in spaceflight
BB Hashemi, JE Penkala, C Vens, H Huls… - The FASEB …, 1999 - Wiley Online Library
Studies of T lymphocyte activation with mitogenic lectins during spaceflight have shown a
dramatic inhibition of activation as measured by DNA synthesis at 72 h, but the mechanism of …
dramatic inhibition of activation as measured by DNA synthesis at 72 h, but the mechanism of …
Extent of radiosensitization by the PARP inhibitor olaparib depends on its dose, the radiation dose and the integrity of the homologous recombination pathway of …
…, M Verheij, MW van den Brekel, C Vens - Radiotherapy and …, 2015 - Elsevier
Background and purpose The PARP inhibitor olaparib is currently tested in clinical phase 1
trials to define safe dose levels in combination with RT. However, certain clinically relevant …
trials to define safe dose levels in combination with RT. However, certain clinically relevant …