3′-azido-3′-deoxythimidine (AZT) is glucuronidated by human UDP-glucuronosyltransferase 2B7 (UGT2B7)

O Barbier, D Turgeon, C Girard, MD Green… - Drug Metabolism and …, 2000 - ASPET
3′-Azido-3′-deoxythymidine (AZT) is frequently prescribed to patients infected with the
human immunodeficiency virus. After absorption, AZT is rapidly metabolized into 3′-azido-3′-…

Clinical characterization of late-and very late-onset first psychotic episode in psychiatric inpatients

C Girard, M Simard - The American Journal of Geriatric Psychiatry, 2008 - Elsevier
Objectives The goals of this study were to investigate the prevalence and initial symptoms of
the late-onset schizophrenia (LOS: >40 years) and very-late-onset schizophrenia-like …

N-Glycosylation and Residue 96 Are Involved in the Functional Properties of UDP-Glucuronosyltransferase Enzymes,

O Barbier, C Girard, R Breton, A Bélanger… - Biochemistry, 2000 - ACS Publications
The recent cloning of several human and monkey UDP-glucuronosyltransferase (UGT) 2B
proteins has allowed the characterization of these steroid metabolic enzymes. However, …

Human uridine diphosphate-glucuronosyltransferase UGT2B7 conjugates mineralocorticoid and glucocorticoid metabolites

C Girard, O Barbier, G Veilleux, M El-Alfy… - …, 2003 - academic.oup.com
Mineralocorticoid and glucocorticoid hormones are metabolized as glucuronide conjugates.
Using labeled [ 14 C]uridine diphosphate glucuronic acid and microsomal preparations from …

Late-onset-psychosis: cognition

C Girard, M Simard, R Noiseux, L Laplante… - International …, 2011 - cambridge.org
Background: The objectives of the study were to characterize and compare the cognitive profile
and natural evolution of patients presenting late-onset psychotic symptoms (LOPS: onset …

Are temperate mixedwood forests perceived by birds as a distinct forest type?

C Girard, M Darveau, JPL Savard… - Canadian journal of …, 2004 - cdnsciencepub.com
Forestry practices used in mixedwood forests have led to a reduction of the availability of
mixedwood stands and to a simplification of the forest mosaic, with unknown consequences on …

Use of perifusion to assess in vitro the functional integrity of interrenal tissue in teleost fish from polluted sites

JC Brodeur, C Girard, A Hontela - … Toxicology and Chemistry …, 1997 - Wiley Online Library
A perifusion procedure adapted to field studies with fish was developed to assess in vitro the
functional integrity of the cortisol‐secreting interrenal tissue, which is distributed within the …

Isolation and characterization of the monkey UGT2B30 gene that encodes a uridine diphosphate-glucuronosyltransferase enzyme active on mineralocorticoid …

C Girard, O Barbier, D Turgeon… - Biochemical …, 2002 - portlandpress.com
The present study reports the genomic organization and the characterization of a novel
cynomolgus monkey UDP-glucuronosyltransferase (UGT) enzyme, UGT2B30. UGT enzymes are …

Invasive plant control by livestock: From targeted eradication to ecosystem restoration

GS Kleppel, CB Girard, S Caggiano… - Ecological …, 2011 - muse.jhu.edu
Restoration Notes have been a distinguishing feature of Ecological Restoration for more than
25 years. This section is geared toward introducing innovative research, tools, technologies…

[HTML][HTML] Elderly patients with very late-onset schizophrenia-like psychosis and early-onset schizophrenia: Cross-sectional and retrospective clinical findings

C Girard, M Simard - Open Journal of Psychiatry, 2012 - scirp.org
Objectives: The aim of this study was to characterize the symptoms at onset/past and current
symptoms of patients with Very Late-Onset Schizophrenia-Like Psychosis (VLOSLP; first …