Decrease in processing speed due to increased resistance and capacitance delay is a
major obstacle for the down-scaling of electronics 1 , 2 – 3 . Minimizing the dimensions of …

The synthesis and biological activity of a series of new 1β-methylcarbapenems 1a–g
containing 5′-isoxazolopyrrolidin-3′-ylthio derivatives as C-2 side chain are described. Most …

Mitsugumin 53 (MG53) negatively regulates skeletal myogenesis by targeting insulin receptor
substrate 1 (IRS-1). Here, we show that MG53 is an ubiquitin E3 ligase that induces IRS-1 …

Tumor angiogenesis is required for tumor development and is stimulated by angiogenic
inducers like VEGF (vascular endothelial growth factor). Our previous study demonstrated that …

Iron is a widely used catalyst for the growth of carbon nanotubes (CNTs) or carbon nanofibers
(CNFs) by catalytic chemical vapor deposition. However, both Fe and Fe–C compounds (…

To unravel the roles of LXRs in inflammation and immunity, we examined the function of
LXRs in development of IFN-γ-mediated inflammation using cultured rat brain astrocytes. LXR …

Since detergent‐resistant lipid rafts are involved in pathogen invasion, cholesterol
homeostasis, angiogenesis, neurodegenerative diseases and signal transduction, protein …

Hypoxia-inducible factor 1α (HIF-1α) is rapidly degraded by the ubiquitin-proteasome pathway
under normoxic conditions. Ubiquitination of HIF-1α is mediated by interaction with von …

Flexible and stretchable optoelectronic devices can be potentially applied in displays, biosensors,
biomedicine, robotics, and energy generation. The use of nanomaterials with superior …

Mice with a knock-in mutation (Y524S) in the type I ryanodine receptor (Ryr1), a mutation
analogous to the Y522S mutation that is associated with malignant hyperthermia in humans, …