Tolvaptan for improvement of hepatic edema: a phase 3, multicenter, randomized, double‐blind, placebo‐controlled trial
…, S Kawazoe, K Kajimura, T Saito, C Okuse… - Hepatology …, 2014 - Wiley Online Library
Aim Hepatic edema is manifested by ascites, lower limb edema and intolerable symptoms.
Some patients insufficiently respond to the conventional diuretic therapy. Therefore, a novel …
Some patients insufficiently respond to the conventional diuretic therapy. Therefore, a novel …
Distribution of hepatitis B virus genotypes among patients with chronic infection in Japan shifting toward an increase of genotype A
…, S Kawata, E Tanaka, N Izumi, C Okuse… - Journal of clinical …, 2009 - Am Soc Microbiol
Acute hepatitis B virus (HBV) infection has been increasing through promiscuous sexual
contacts, and HBV genotype A (HBV/A) is frequent in patients with acute hepatitis B (AHB) in …
contacts, and HBV genotype A (HBV/A) is frequent in patients with acute hepatitis B (AHB) in …
Higher discontinuation and lower survival rates are likely in elderly Japanese patients with advanced hepatocellular carcinoma receiving sorafenib
…, S Kobayashi, S Ohkawa, C Okuse… - Hepatology …, 2011 - Wiley Online Library
Aim: Sorafenib is approved for the treatment of advanced hepatocellular carcinoma (HCC)
in Japan; however, its tolerability and efficacy in elderly patients with HCC have not been …
in Japan; however, its tolerability and efficacy in elderly patients with HCC have not been …
[HTML][HTML] Pancreatic involvement in chronic viral hepatitis
…, K Hashizume, C Okuse, N Okuse… - World Journal of …, 2005 - ncbi.nlm.nih.gov
AIM: To elucidate the frequency and characteristics of pancreatic disorders in the course of
chronic viral hepatitis. METHODS: We prospectively assessed the serum pancreatic enzyme …
chronic viral hepatitis. METHODS: We prospectively assessed the serum pancreatic enzyme …
Insufficient radiofrequency ablation therapy may induce further malignant transformation of hepatocellular carcinoma
…, Y Katakura, K Matsunaga, T Ishii, C Okuse… - Hepatology …, 2008 - Springer
Background Radiofrequency ablation (RFA) for hepatocellular carcinoma (HCC) is a
thermoablative technique to kill tumor tissue by generating areas of coagulative necrosis. Recent …
thermoablative technique to kill tumor tissue by generating areas of coagulative necrosis. Recent …
[HTML][HTML] Randomized, phase II trial of sequential hepatic arterial infusion chemotherapy and sorafenib versus sorafenib alone as initial therapy for advanced …
…, T Hatanaka, D Takizawa, K Matsunaga, C Okuse… - BMC cancer, 2019 - Springer
Background The efficacy of hepatic arterial infusion chemotherapy (HAIC) for advanced
hepatocellular carcinoma (HCC) remains unclear. We conducted a multi-center randomized …
hepatocellular carcinoma (HCC) remains unclear. We conducted a multi-center randomized …
[HTML][HTML] Risk factors for retinopathy associated with interferon α-2b and ribavirin combination therapy in patients with chronic hepatitis C
C Okuse, H Yotsuyanagi, Y Nagase… - World Journal of …, 2006 - ncbi.nlm.nih.gov
AIM: To elucidate the frequency and risk factors for retinopathy in patients with chronic
hepatitis C who are treated by interferon-ribavirin combination therapy. METHODS: We …
hepatitis C who are treated by interferon-ribavirin combination therapy. METHODS: We …
[HTML][HTML] Modified response evaluation criteria in solid tumors is superior to response evaluation criteria in solid tumors for assessment of responses to sorafenib in …
…, K Numata, K Tanaka, K Matsunaga, C Okuse… - BMC Research …, 2015 - Springer
Background Modified response evaluation criteria in solid tumors (mRECIST) and RECIST
are used to assess the effect of treatment with targeted agents for hepatocellular carcinoma (…
are used to assess the effect of treatment with targeted agents for hepatocellular carcinoma (…
[HTML][HTML] Correlation between hepatic blood flow and liver function in alcoholic liver cirrhosis
…, K Matsunaga, N Matsumoto, C Okuse… - World Journal of …, 2014 - ncbi.nlm.nih.gov
AIM: To elucidate the correlation between hepatic blood flow and liver function in alcoholic
liver cirrhosis (AL-LC). METHODS: The subjects included 35 patients with AL-LC (34 men, 1 …
liver cirrhosis (AL-LC). METHODS: The subjects included 35 patients with AL-LC (34 men, 1 …
Distinct geographic distributions of hepatitis B virus genotypes in patients with acute infection in Japan
H Yotsuyanagi, C Okuse, K Yasuda… - Journal of medical …, 2005 - Wiley Online Library
Genotypes of hepatitis B virus (HBV) were determined in 145 patients with acute hepatitis B
from various districts in Japan to establish their geographic distribution and evaluating the …
from various districts in Japan to establish their geographic distribution and evaluating the …