CYP3A4 induction by drugs: correlation between a pregnane X receptor reporter gene assay and CYP3A4 expression in human hepatocytes

…, T Burn, J Lin, M Sinz, G Hamilton, C Rizzo… - Drug Metabolism and …, 2002 - ASPET
Induction of cytochrome P450 3A4 (CYP3A4) is determined typically by employing primary
culture of human hepatocytes and measuring CYP3A4 mRNA, protein and microsomal activity…

Apoptosis mediated by HIV protease is preceded by cleavage of Bcl-2.

PR Strack, MW Frey, CJ Rizzo… - Proceedings of the …, 1996 - National Acad Sciences
Expression of the human immunodeficiency virus type 1 (HIV) protease in cultured cells
leads to apoptosis, preceded by cleavage of bcl-2, a key negative regulator of cell death. In …

Genotypic correlates of phenotypic resistance to efavirenz in virus isolates from patients failing nonnucleoside reverse transcriptase inhibitor therapy

…, K Gallagher, H Scarnati, R Tritch, C Rizzo - Journal of …, 2001 - Am Soc Microbiol
Efavirenz (also known as DMP 266 or SUSTIVA) is a potent nonnucleoside inhibitor of
human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) activity and of HIV-1 …

[HTML][HTML] Transcriptome profiling of the rice blast fungus during invasive plant infection and in vitro stresses

SM Mathioni, A Beló, CJ Rizzo, RA Dean, NM Donofrio - Bmc Genomics, 2011 - Springer
Background Rice blast is the most threatening disease to cultivated rice. Magnaporthe oryzae,
its causal agent, is likely to encounter environmental challenges during invasive growth in …

Outbreak of acute rheumatic fever in northeast Ohio

B Congeni, C Rizzo, J Congeni, VV Sreenivasan - The Journal of pediatrics, 1987 - Elsevier
An outbreak of acute rheumatic fever in 23 patients was seen in northeastern Ohio in 1986,
with polyarthritis (78%) and carditis (30%) the major manifestations. Results of a …

[HTML][HTML] SENTINEL1: Two-season study of respiratory syncytial virus hospitalizations among US infants born at 29 to 35 weeks' gestational age not receiving …

…, VR Kumar, KK McLaurin, CP Rizzo… - American journal of …, 2020 - thieme-connect.com
Objective The SENTINEL1 observational study characterized confirmed respiratory syncytial
virus hospitalizations (RSVH) among US preterm infants born at 29 to 35 weeks' gestational …

Medically attended illness due to respiratory syncytial virus infection among infants born in the United States between 2016 and 2020

…, WV La Via, CB Nelson, C Rizzo… - The Journal of …, 2022 - academic.oup.com
Background Respiratory syncytial virus (RSV) is a leading cause of infant hospitalization in
the United States. Preterm infants and those with select comorbidities are at highest risk of …

Molecular basis of HIV-1 protease drug resistance: structural analysis of mutant proteases complexed with cyclic urea inhibitors

…, RM Klabe, DD McCabe, JL Duke, CJ Rizzo… - Biochemistry, 1997 - ACS Publications
In cell cultures, the key residues associated with HIV-1 resistance to cyclic urea-based HIV-1
protease (PR) inhibitors are Val82 and Ile84 of HIV-1 PR. To gain an understanding of how …

Athletic trainers have a place in interprofessional education and practice

CS Rizzo, AP Breitbach… - Journal of interprofessional …, 2015 - Taylor & Francis
Athletic trainers (ATs) are healthcare providers who work in collaboration with physicians,
nurses, physical therapists and others to provide care to physically active individuals. Founded …

Inequalities in health impact of alternative reimbursement pathways for nirsevimab in the United States

GB Gomez, CB Nelson, C Rizzo… - The Journal of …, 2022 - academic.oup.com
The target populations and financing mechanisms for a new health technology may affect
health inequalities in access and impact. We projected the distributional consequences of …