Effect of culture time on the basal expression levels of drug transporters in sandwich-cultured primary rat hepatocytes
EH Tchaparian, JS Houghton, C Uyeda… - Drug metabolism and …, 2011 - ASPET
Sandwich-cultured rat hepatocytes are used in drug discovery for pharmacological and
toxicological assessment of drug candidates, yet their utility as a functional model for drug …
toxicological assessment of drug candidates, yet their utility as a functional model for drug …
Discovery and molecular basis of potent noncovalent inhibitors of fatty acid amide hydrolase (FAAH)
…, H Xu, M Lindstrom, G Xu, C Uyeda… - Proceedings of the …, 2011 - National Acad Sciences
Fatty acid amide hydrolase (FAAH), an amidase-signature family member, is an integral
membrane enzyme that degrades lipid amides including the endogenous cannabinoid …
membrane enzyme that degrades lipid amides including the endogenous cannabinoid …
Design of 1-piperazinyl-4-arylphthalazines as potent Smoothened antagonists
…, J Orf, JP Powers, M Rong, MM Toteva, C Uyeda… - Bioorganic & medicinal …, 2010 - Elsevier
The Hedgehog (Hh) signaling pathway regulates cell proliferation and differentiation in
developing tissues, and abnormal activation of the Hh pathway has been linked to several tumor …
developing tissues, and abnormal activation of the Hh pathway has been linked to several tumor …
Application of automated dried blood spot sampling and LC–MS/MS for pharmacokinetic studies of AMG 517 in rats
C Uyeda, R Pham, S Fide, K Henne, G Xu, M Soto… - Bioanalysis, 2011 - Future Science
Background: The use of dried blood spot (DBS) sampling technique is of particular interest
for drug discovery pharmacokinetic studies due to the small blood volume requirement. In …
for drug discovery pharmacokinetic studies due to the small blood volume requirement. In …
Application of DBS sampling in combination with LC–MS/MS for pharmacokinetic evaluation of a compound with species-specific blood-to-plasma partitioning
G Xu, JS Chen, R Phadnis, T Huang, C Uyeda, M Soto… - Bioanalysis, 2012 - Future Science
Background: Dried blood spot (DBS) sampling in combination with LC–MS/MS has been
used increasingly in drug discovery for quantitative analysis to support pharmacokinetic (PK) …
used increasingly in drug discovery for quantitative analysis to support pharmacokinetic (PK) …
The evolution of energetic scaling across the vertebrate tree of life
Metabolism is the link between ecology and physiology—it dictates the flow of energy through
individuals and across trophic levels. Much of the predictive power of metabolic theories of …
individuals and across trophic levels. Much of the predictive power of metabolic theories of …
Distribution of wetland tree species in relation to a flooding gradient and backwater versus streamside location in Arkansas, USA
EE Dale Jr, S Ware - Journal of the Torrey Botanical Society, 2004 - JSTOR
Most of Arkansas is outside the normal geographic range of several bottomland hardwood
species important in floodplain forests of the southeastern United States. Other species …
species important in floodplain forests of the southeastern United States. Other species …
[PDF][PDF] Additional records of distribution and hosts for the bat bug, Cimex pilosellus in Arkansas
TW Steward, VR McDaniel… - Journal of the Arkansas …, 1986 - scholarworks.uark.edu
… The contributions ofbiologists Clyde Gates (Corp ofEngineers) and Craig Uyeda (Game
and Fish Commission) are noted with appreciation. Gates and Uyeda stayed with the survey …
and Fish Commission) are noted with appreciation. Gates and Uyeda stayed with the survey …
[PDF][PDF] Arkansas Natural Heritage Commission Correspondence
A Attachment - Citeseer
The severe accident consequence analysis was carried out with the Melcor Accident
Consequence Code System (Reference E. 1-1). MACCS2 simulates the impact of severe accidents …
Consequence Code System (Reference E. 1-1). MACCS2 simulates the impact of severe accidents …
[PDF][PDF] Arkansas Academy off Science
JH PECK, JD CLARK, T SHELDON… - Academy …, 1986 - scholarworks.uark.edu
… The contributions ofbiologists Clyde Gates (Corp ofEngineers) and Craig Uyeda (Game
and Fish Commission) are noted with appreciation. Gates and Uyeda stayed with the survey …
and Fish Commission) are noted with appreciation. Gates and Uyeda stayed with the survey …