… This may be due to the comparatively lower stability of these ligands in aqueous media
compared with rosiglitazone and binding to the serum albumin (Grant, D., unpublished …

… Our research was supported in part by grants from National lnstitute of Environmental
Health Sciences ES02710, NlEHS Superfund Basic Research Program ES04699, and the …

Soluble epoxide hydrolase (sEH) hydrolyzes a wide variety of endogenous and exogenous
epoxides. Many of these epoxides are believed to be formed by cytochrome P450 …

Despite recent advances in analytical and computational chemistry, lipid identification
remains a significant challenge in lipidomics. Ion-mobility spectrometry provides an accurate …

… GST-1 was purified from the IVF,, strain as described in Grant and Matsumura (25) for the
Rock strain. There was no difference in the isoelectric point of GST-1 in the two strains, both …

Human soluble epoxide hydrolase (hsEH) metabolizes a variety of epoxides to the corresponding
vicinal diols. Arachidonic and linoleic acid epoxides are thought to be endogenous …

Direct comparison of the amino acid sequences of microsomal and soluble epoxide hydrolase
superficially indicates that these enzymes are unrelated. Both proteins, however, share …

Single nucleotide polymorphisms (SNPs) in the human EPHX2 gene have recently been
implicated in susceptibility to cardiovascular disease, including stroke. EPHX2 encodes for …

… The authors acknowledge support for this work by a grant from Pfizer Inc., Groton, CT, the
University of Connecticut Foundation, and by an American Foundation for Pharmaceutical …

… 26 800) cross-react identically with an antiserum prepared against purified GST-lb (Grant
1991). This antiserum does not cross-react with GST-2 (homodimer, subunit mol. wt. …