Mitochondrial localization of the Parkinson's disease related protein DJ-1: implications for pathogenesis
… DJ-1, we generated three highly specific antibodies to DJ-1 protein and investigated the
subcellular localization of endogenous DJ-… DJ-1 in mitochondria and the potential function of DJ-…
subcellular localization of endogenous DJ-… DJ-1 in mitochondria and the potential function of DJ-…
Association of DJ-1 and parkin mediated by pathogenic DJ-1 mutations and oxidative stress
… Here, we show that pathogenic mutant forms of DJ-1 specifically but … DJ-1 mutants exhibit
impairments in homo-dimer formation, suggesting that parkin may bind to monomeric DJ-1. …
impairments in homo-dimer formation, suggesting that parkin may bind to monomeric DJ-1. …
PINK1-dependent recruitment of Parkin to mitochondria in mitophagy
… Thus, whatever the functional nature of DJ-1 interaction with Parkin and PINK1 may be,
our data exclude the possibility that DJ-1 is required for the PINK1-dependent translocation of …
our data exclude the possibility that DJ-1 is required for the PINK1-dependent translocation of …
[HTML][HTML] AXOR12, a novel human G protein-coupled receptor, activated by the peptide KiSS-1
…, NA Elshourbagy, D Michalovich, DJ Moore… - Journal of Biological …, 2001 - ASBMB
A novel human G protein-coupled receptor named AXOR12, exhibiting 81% homology to
the rat orphan receptor GPR54, was cloned from a human brain cDNA library. Heterologous …
the rat orphan receptor GPR54, was cloned from a human brain cDNA library. Heterologous …
Molecular pathophysiology of Parkinson's disease
… The crystal structure of human DJ-1 has been resolved and reveals a flavodoxin-like fold
similar to the bacterial protease PH1704 and the stressinducible molecular chaperone Hsp31, …
similar to the bacterial protease PH1704 and the stressinducible molecular chaperone Hsp31, …
Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity
Mutations in the leucine-rich repeat kinase 2 gene (LRRK2) cause late-onset Parkinson's
disease (PD) with a clinical appearance indistinguishable from idiopathic PD. Initial studies …
disease (PD) with a clinical appearance indistinguishable from idiopathic PD. Initial studies …
The impact of HIV-associated neuropsychological impairment on everyday functioning
…, TD Marcotte, MR Mindt, J Sadek, DJ Moore… - Journal of the …, 2004 - cambridge.org
HIV-1 infection can be associated with neuropsychological (NP) deficits ranging from subtle
to severe. The purpose of this study was to evaluate the functional, or “real-world” impact of …
to severe. The purpose of this study was to evaluate the functional, or “real-world” impact of …
Public service advertisements: Emotions and empathy guide prosocial behavior
RP Bagozzi, DJ Moore - Journal of marketing, 1994 - journals.sagepub.com
The authors develop and test a theory of how public service advertisements function to induce
helping responses. Building on Lazarus's general theory of emotion and adaptation, they …
helping responses. Building on Lazarus's general theory of emotion and adaptation, they …
Complete Gene Map of the Plastid-like DNA of the Malaria ParasitePlasmodium falciparum
…, A Roy, A Whyte, M Strath, DJ Moore, PW Moore… - Journal of molecular …, 1996 - Elsevier
Malaria parasites, and other parasitic protists of the Phylum Apicomplexa, carry a plastid-like
genome with greatly reduced sequence complexity. This 35 kb DNA circle resembles the …
genome with greatly reduced sequence complexity. This 35 kb DNA circle resembles the …
[HTML][HTML] Cognitive neuropsychology of HIV-associated neurocognitive disorders
Advances in the treatment of the human immunodeficiency virus (HIV) have dramatically
improved survival rates over the past 10 years, but HIV-associated neurocognitive disorders (…
improved survival rates over the past 10 years, but HIV-associated neurocognitive disorders (…