User profiles for D. J. Murry

DJ Murry

UNMC
Verified email at unmc.edu
Cited by 6561

Impact of nutrition on pharmacokinetics of anti‐neoplastic agents

DJ Murry, L Riva, DG Poplack - International journal of cancer, 1998 - Wiley Online Library
It has been estimated that approximately 80% of the world's pediatric population lives in
countries with limited resources, and that 43% of these children are malnourished. In children …

Clinical pharmacology of encapsulated sustained-release cytarabine

DJ Murry, SM Blaney - Annals of Pharmacotherapy, 2000 - journals.sagepub.com
BACKGROUND: The therapeutic effectiveness of chemotherapy is often limited by the
inability to sustain cytotoxic concentrations at the tumor site. Cytarabine liposome injection (…

Light induces phenylpropanoid metabolism in Arabidopsis roots

MR Hemm, SD Rider, J Ogas, DJ Murry… - The Plant …, 2004 - Wiley Online Library
Experiments have shown that many phenylpropanoid genes are highly expressed in light‐grown
Arabidopsis roots. Studies employing reporter gene constructs have indicated that the …

Methylphenidate is stereoselectively hydrolyzed by human carboxylesterase CES1A1

Z Sun, DJ Murry, SP Sanghani, WI Davis… - … of Pharmacology and …, 2004 - ASPET
Methylphenidate is an important stimulant prescribed to treat attention-deficit hyperactivity
disorder. It has two chiral centers, but most current commercial formulations consist of the …

Chemically induced degradation of CDK9 by a proteolysis targeting chimera (PROTAC)

…, M Abid, YA Sonawane, M Zahid, DJ Murry… - Chemical …, 2017 - pubs.rsc.org
Cyclin-dependent kinase 9 (CDK9), a member of the cyclin-dependent protein kinase (CDK)
family, is involved in transcriptional elongation of several target genes. CDK9 is …

The sesquiterpene lactone parthenolide in combination with docetaxel reduces metastasis and improves survival in a xenograft model of breast cancer

…, Y Roman, C Sheridan, RA Campbell, DJ Murry… - Molecular cancer …, 2005 - AACR
Parthenolide, a sesquiterpene lactone, shows antitumor activity in vitro, which correlates with
its ability to inhibit the DNA binding of the antiapoptotic transcription factor nuclear factor κB …

[HTML][HTML] Phase I and pharmacokinetic study of sorafenib in patients with hepatic or renal dysfunction: CALGB 60301

AA Miller, DJ Murry, K Owzar, DR Hollis… - Journal of Clinical …, 2009 - ncbi.nlm.nih.gov
Murry, Kouros Owzar, Donna R. Hollis, Ghassan Abou-Alfa, Lionel D. Lewis, Mark J. …
Murry, Kouros Owzar, Donna R. Hollis, Erin B. Kennedy, Ghassan Abou-Alfa, Mark J …

Hydrolysis of capecitabine to 5′-deoxy-5-fluorocytidine by human carboxylesterases and inhibition by loperamide

…, WI Davis, TD Hurley, Z Sun, DJ Murry… - … of Pharmacology and …, 2005 - ASPET
Capecitabine is an oral prodrug of 5-fluorouracil that is indicated for the treatment of breast
and colorectal cancers. A three-step in vivo-targeted activation process requiring …

Drug testing in the workplace

HM Phan, K Yoshizuka, DJ Murry… - … : The Journal of Human …, 2012 - Wiley Online Library
Congress passed the Drug‐Free Workplace Act in April 1988, which resulted in the Mandatory
Guidelines for Federal Workplace Drug Testing Programs. The intent was to establish a …

Carboxylesterases expressed in human colon tumor tissue and their role in CPT-11 hydrolysis

…, TB Fredenburg, Z Sun, WI Davis, DJ Murry… - Clinical Cancer …, 2003 - AACR
Purpose: The purpose is to develop new analytical methods to study the expression profile
of CPT-11 carboxylesterases and topoisomerase I in colon tumor samples and understand …