Ergothioneine (ET) is a natural compound which humans and other vertebrates cannot
synthesize themselves; it must be absorbed from food in which it is distributed very unevenly. In …

… blot hybridizations with the cDNA encoding OCT1 are shown in a and b, and control
hybridizations with a cDNA encoding glyceraldehyde-3-phosphate dehydrogenase in c and d. For in …

The extraneuronal monoamine transporter (EMT) corresponds to the classical steroid-sensitivemonoamine
transportmechanism that was first described as “uptake 2 ” in rat heart with …

Variants of the SLC22A4 gene are associated with susceptibility to rheumatoid arthritis and
Crohn's disease. SLC22A4 codes for an integral membrane protein, OCTN1, that has been …

In all vertebrates including mammals, the ergothioneine transporter ETT (obsolete name
OCTN1; human gene symbol SLC22A4) is a powerful and highly specific transporter for the …

Catecholaminergic signaling regulates various physiological functions, such as blood
pressure 1 and is implicated in drug dependence, affective disorders and male aggressive …

The recently identified transport proteins organic cation transporter 1 (OCT1), OCT2, and
extraneuronal monoamine transporter (EMT) accept dopamine, noradrenaline, adrenaline, and …

The study was designed to test the hypothesis that aspirin may stimulate nitric oxide (NO)
release from vascular endothelium, a pivotal factor for maintenance of vascular homeostasis. …

… The recently cloned apical renal transport system for organic cations (OCT2) exists in
dopamine-rich tissues such as kidney and some brain areas (Gründemann, D., Babin-Ebell, J., …

… We have observed organ-specific accumulation of ET, and have cloned and functionally
verified ETT from zebrafish (Bach & Gründemann, unpublished). Since only fungi and …