Impact of CYP2C19 variant genotypes on clinical efficacy of antiplatelet treatment with clopidogrel: systematic review and meta-analysis

…, JW van Werkum, NF Ford, JM Ten Berg, D Taubert - Bmj, 2011 - bmj.com
… , Dirk Taubert group leader1 1Department of Pharmacology, University Hospital of Cologne,
D-50931 Cologne, Germany; 2Department of Biochemistry, Cardiovascular Research …

Absorption, metabolization, and antiplatelet effects of 300-, 600-, and 900-mg loading doses of clopidogrel: results of the ISAR-CHOICE (Intracoronary Stenting and …

N von Beckerath, D Taubert, G Pogatsa-Murray… - Circulation, 2005 - Am Heart Assoc
Background— For patients undergoing percutaneous coronary intervention, the administration
of a clopidogrel loading dose ranging from 300 to 600 mg is currently recommended. It is …

Effects of low habitual cocoa intake on blood pressure and bioactive nitric oxide: a randomized controlled trial

D Taubert, R Roesen, C Lehmann, N Jung, E Schömig - Jama, 2007 - jamanetwork.com
… Normal distribution was assessed by the D'Agostino and Pearson omnibus normality test.
Pairwise … Author Contributions: Taubert had full access to all of the data in the study and takes …

Paraoxonase-1 is a major determinant of clopidogrel efficacy

…, C Waldmann, HG Schmalz, JM Ten Berg, D Taubert - Nature medicine, 2011 - nature.com
… In addition, early stent thrombosis (within 30 d, n = 30) tended to be more frequent than
late or very late stent thrombosis (>30 d, n = 11) in QQ192 subjects as compared with QR192 …

Impact of P‐glycoprotein on clopidogrel absorption

D Taubert, N von Beckerath, G Grimberg… - Clinical …, 2006 - Wiley Online Library
Objective The antiplatelet activity of clopidogrel is characterized by considerable
interindividual differences. Variable intestinal absorption is suggested to contribute to the …

Effect of cocoa and tea intake on blood pressure: a meta-analysis

D Taubert, R Roesen, E Schömig - Archives of internal medicine, 2007 - jamanetwork.com
D Catechin intake might explain the inverse relation between tea consumption and … the
manuscript: Taubert. Critical revision of the manuscript for important intellectual content: Taubert, …

Chocolate and blood pressure in elderly individuals with isolated systolic hypertension

D Taubert, R Berkels, R Roesen, W Klaus - Jama, 2003 - jamanetwork.com
Methods Methods We conducted a randomized crossover trial in 13 otherwise healthy
individuals (6 men and 7 women, aged 55-64 years, with body mass index of 21.9-26.2 […

Pharmacokinetics of clopidogrel after administration of a high loading dose

D Taubert, A Kastrati, S Harlfinger… - Thrombosis and …, 2004 - thieme-connect.com
The adenosine diphosphate (ADP) receptor P2Y12 blocking agent clopidogrel is clinically
proven to be efficient in preventing thrombotic events. However, its therapeutic value is limited …

Dietary sources and antioxidant effects of ergothioneine

J Ey, E Schömig, D Taubert - Journal of agricultural and food …, 2007 - ACS Publications
Ergothioneine is a native membrane-impermeable thiol compound that is specifically
accumulated in cells via the organic cation transporter OCTN1. In humans, OCTN1 and …

Aspirin induces nitric oxide release from vascular endothelium: a novel mechanism of action

D Taubert, R Berkels, N Grosser… - British journal of …, 2004 - Wiley Online Library
The study was designed to test the hypothesis that aspirin may stimulate nitric oxide (NO)
release from vascular endothelium, a pivotal factor for maintenance of vascular homeostasis. …