Molecular and physical mechanisms of first-pass extraction
This is a report of a symposium held at the March 1997 meeting of the American Society for
Pharmacology and Therapeutics in San Diego. Our understanding of the events that control …
Pharmacology and Therapeutics in San Diego. Our understanding of the events that control …
[PDF][PDF] Meckel's diverticulum
DK Turgeon, JL Barnett - 1990 - deepblue.lib.umich.edu
Meckel's diverticulum is the most common congenital anomaly of the gastrointestinal tract,
occurring in I-3'V of the population, based on autopsy studies (1)(Kig. I). It wa. s first described …
occurring in I-3'V of the population, based on autopsy studies (1)(Kig. I). It wa. s first described …
Common and scientific names of aquatic invertebrates from the United States and Canada: Mollusks
DD Turgeon, JF Quinn, AE Bogan, EV Coan… - 1998 - pubs.er.usgs.gov
This edition of Common and Scientific Names of Invertebrates from the United States and
Canada: Mollusks represents the efforts of 15 molluscan taxonomic specialists in compiling a …
Canada: Mollusks represents the efforts of 15 molluscan taxonomic specialists in compiling a …
Role of intestinal P‐glycoprotein (mdr1) in interpatient variation in the oral bioavailability of cyclosporine
…, AB Leichtman, H Hsiao, DK Turgeon… - Clinical …, 1997 - Wiley Online Library
Interpatient differences in the oral clearance of cyclosporine (INN, ciclosporin) have been
partially attributed to variation in the activity of a single liver enzyme termed CYP3A4. Recently …
partially attributed to variation in the activity of a single liver enzyme termed CYP3A4. Recently …
Difluoromethylornithine plus sulindac for the prevention of sporadic colorectal adenomas: a randomized placebo-controlled, double-blind trial
…, J McCracken, CG Albers, DJ Ahnen, DK Turgeon… - Cancer prevention …, 2008 - AACR
Preclinical studies of chemoprevention drugs given in combination at low doses show
remarkable efficacy in preventing adenomas with little additional toxicities, suggesting a strategy …
remarkable efficacy in preventing adenomas with little additional toxicities, suggesting a strategy …
Characterization and regulation of UDP-glucuronosyltransferases in steroid target tissues
…, A Tchernof, G Bélanger, D Turgeon… - The Journal of steroid …, 1998 - Elsevier
Conjugation of compounds by glucuronidation is a pathway found in all vertebrates studied
to date. Although, it is widely recognized that the liver is a major site of glucuronidation, it is …
to date. Although, it is widely recognized that the liver is a major site of glucuronidation, it is …
Phase IIa clinical trial of curcumin for the prevention of colorectal neoplasia
RE Carroll, RV Benya, DK Turgeon, S Vareed… - Cancer prevention …, 2011 - AACR
Curcumin is derived from the spice tumeric and has antiinflammatory and antineoplastic
effects in vitro and in animal models, including preventing aberrant crypt foci (ACF) and …
effects in vitro and in animal models, including preventing aberrant crypt foci (ACF) and …
Relative enzymatic activity, protein stability, and tissue distribution of human steroid-metabolizing UGT2B subfamily members
D Turgeon, JS Carrier, E Lévesque, DW Hum… - …, 2001 - academic.oup.com
… Treatment of stable cells with actinomycin D reveals that UGT2B transcripts are stable for 12
… HK293 cell lines stably expressing UGT2B4(D 458 ), UGT2B15(D 85 ), and UGT2B17 were …
… HK293 cell lines stably expressing UGT2B4(D 458 ), UGT2B15(D 85 ), and UGT2B17 were …
[HTML][HTML] Efficacy of transoral fundoplication vs omeprazole for treatment of regurgitation in a randomized controlled trial
…, MA Burch, WS Melvin, KM Reavis, DG Turgeon… - Gastroenterology, 2015 - Elsevier
Background & Aims Transoral esophagogastric fundoplication (TF) can decrease or eliminate
features of gastroesophageal reflux disease (GERD) in some patients whose symptoms …
features of gastroesophageal reflux disease (GERD) in some patients whose symptoms …
Plasma glycoprotein profiling for colorectal cancer biomarker identification by lectin glycoarray and lectin blot
…, M Tuck, G Jin, MT Ruffin, DK Turgeon… - Journal of proteome …, 2008 - ACS Publications
Colorectal cancer (CRC) remains a major worldwide cause of cancer-related morbidity and
mortality largely due to the insidious onset of the disease. The current clinical procedures …
mortality largely due to the insidious onset of the disease. The current clinical procedures …